YEATS domain: Linking histone crotonylation to gene regulation

Recent research reveals that the YEATS domains preferentially recognize crotonylated lysines on histones. Here, we discuss the molecular mechanisms that enable this recognition and the biological significances of this interaction. The dynamics of histone crotonylation and its potential roles in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yuanyuan, Zhao, Dan, Chen, Zhonglei, Li, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Point-of-View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402991/
https://www.ncbi.nlm.nih.gov/pubmed/27661789
http://dx.doi.org/10.1080/21541264.2016.1239602
_version_ 1783231343567568896
author Li, Yuanyuan
Zhao, Dan
Chen, Zhonglei
Li, Haitao
author_facet Li, Yuanyuan
Zhao, Dan
Chen, Zhonglei
Li, Haitao
author_sort Li, Yuanyuan
collection PubMed
description Recent research reveals that the YEATS domains preferentially recognize crotonylated lysines on histones. Here, we discuss the molecular mechanisms that enable this recognition and the biological significances of this interaction. The dynamics of histone crotonylation and its potential roles in the regulation of gene expression will also be discussed.
format Online
Article
Text
id pubmed-5402991
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Taylor & Francis
record_format MEDLINE/PubMed
spelling pubmed-54029912017-04-28 YEATS domain: Linking histone crotonylation to gene regulation Li, Yuanyuan Zhao, Dan Chen, Zhonglei Li, Haitao Transcription Point-of-View Recent research reveals that the YEATS domains preferentially recognize crotonylated lysines on histones. Here, we discuss the molecular mechanisms that enable this recognition and the biological significances of this interaction. The dynamics of histone crotonylation and its potential roles in the regulation of gene expression will also be discussed. Taylor & Francis 2016-09-23 /pmc/articles/PMC5402991/ /pubmed/27661789 http://dx.doi.org/10.1080/21541264.2016.1239602 Text en © 2017 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License http://creativecommons.org/licenses/by-nc/3.0/, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Point-of-View
Li, Yuanyuan
Zhao, Dan
Chen, Zhonglei
Li, Haitao
YEATS domain: Linking histone crotonylation to gene regulation
title YEATS domain: Linking histone crotonylation to gene regulation
title_full YEATS domain: Linking histone crotonylation to gene regulation
title_fullStr YEATS domain: Linking histone crotonylation to gene regulation
title_full_unstemmed YEATS domain: Linking histone crotonylation to gene regulation
title_short YEATS domain: Linking histone crotonylation to gene regulation
title_sort yeats domain: linking histone crotonylation to gene regulation
topic Point-of-View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402991/
https://www.ncbi.nlm.nih.gov/pubmed/27661789
http://dx.doi.org/10.1080/21541264.2016.1239602
work_keys_str_mv AT liyuanyuan yeatsdomainlinkinghistonecrotonylationtogeneregulation
AT zhaodan yeatsdomainlinkinghistonecrotonylationtogeneregulation
AT chenzhonglei yeatsdomainlinkinghistonecrotonylationtogeneregulation
AT lihaitao yeatsdomainlinkinghistonecrotonylationtogeneregulation

Ejemplares similares