mcr-1 Colistin Resistance in ESBL-Producing Klebsiella pneumoniae, France

We report intestinal carriage of an extended-spectrum β-lactamase−producing Klebsiella pneumoniae strain with high-level resistance to colistin (MIC 24 mg/L) in a patient in France who had been hospitalized for fungal meningitis. The strain had the mcr-1 plasmid gene and an inactivated mgrB gene, wh...

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Autores principales: Caspar, Yvan, Maillet, Mylène, Pavese, Patricia, Francony, Gilles, Brion, Jean-Paul, Mallaret, Marie-Reine, Bonnet, Richard, Robin, Frédéric, Beyrouthy, Racha, Maurin, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403025/
https://www.ncbi.nlm.nih.gov/pubmed/28418313
http://dx.doi.org/10.3201/eid2305.161942
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author Caspar, Yvan
Maillet, Mylène
Pavese, Patricia
Francony, Gilles
Brion, Jean-Paul
Mallaret, Marie-Reine
Bonnet, Richard
Robin, Frédéric
Beyrouthy, Racha
Maurin, Max
author_facet Caspar, Yvan
Maillet, Mylène
Pavese, Patricia
Francony, Gilles
Brion, Jean-Paul
Mallaret, Marie-Reine
Bonnet, Richard
Robin, Frédéric
Beyrouthy, Racha
Maurin, Max
author_sort Caspar, Yvan
collection PubMed
description We report intestinal carriage of an extended-spectrum β-lactamase−producing Klebsiella pneumoniae strain with high-level resistance to colistin (MIC 24 mg/L) in a patient in France who had been hospitalized for fungal meningitis. The strain had the mcr-1 plasmid gene and an inactivated mgrB gene, which are associated with colistin resistance.
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spelling pubmed-54030252017-05-12 mcr-1 Colistin Resistance in ESBL-Producing Klebsiella pneumoniae, France Caspar, Yvan Maillet, Mylène Pavese, Patricia Francony, Gilles Brion, Jean-Paul Mallaret, Marie-Reine Bonnet, Richard Robin, Frédéric Beyrouthy, Racha Maurin, Max Emerg Infect Dis Research Letter We report intestinal carriage of an extended-spectrum β-lactamase−producing Klebsiella pneumoniae strain with high-level resistance to colistin (MIC 24 mg/L) in a patient in France who had been hospitalized for fungal meningitis. The strain had the mcr-1 plasmid gene and an inactivated mgrB gene, which are associated with colistin resistance. Centers for Disease Control and Prevention 2017-05 /pmc/articles/PMC5403025/ /pubmed/28418313 http://dx.doi.org/10.3201/eid2305.161942 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Caspar, Yvan
Maillet, Mylène
Pavese, Patricia
Francony, Gilles
Brion, Jean-Paul
Mallaret, Marie-Reine
Bonnet, Richard
Robin, Frédéric
Beyrouthy, Racha
Maurin, Max
mcr-1 Colistin Resistance in ESBL-Producing Klebsiella pneumoniae, France
title mcr-1 Colistin Resistance in ESBL-Producing Klebsiella pneumoniae, France
title_full mcr-1 Colistin Resistance in ESBL-Producing Klebsiella pneumoniae, France
title_fullStr mcr-1 Colistin Resistance in ESBL-Producing Klebsiella pneumoniae, France
title_full_unstemmed mcr-1 Colistin Resistance in ESBL-Producing Klebsiella pneumoniae, France
title_short mcr-1 Colistin Resistance in ESBL-Producing Klebsiella pneumoniae, France
title_sort mcr-1 colistin resistance in esbl-producing klebsiella pneumoniae, france
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403025/
https://www.ncbi.nlm.nih.gov/pubmed/28418313
http://dx.doi.org/10.3201/eid2305.161942
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