Phenotypic and Genotypic Shifts in Hepatitis B Virus in Treatment-Naive Patients, Taiwan, 2008–2012

We examined the characteristic changes of hepatitis B virus (HBV) in antiviral drug treatment–naive patients referred for pretreatment evaluation in Taiwan during 2008–2012. Over time, we observed substantial decreases in the prevalence of HBV e antigen (HBeAg) and increasing prevalence of the preco...

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Autores principales: Yeh, Chau-Ting, Liang, Kung-Hao, Chang, Ming-Ling, Hsu, Chao-Wei, Chen, Yi-Cheng, Lin, Chih-Lang, Lin, Wey-Ran, Lai, Ming-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403058/
https://www.ncbi.nlm.nih.gov/pubmed/28418295
http://dx.doi.org/10.3201/eid2305.161894
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author Yeh, Chau-Ting
Liang, Kung-Hao
Chang, Ming-Ling
Hsu, Chao-Wei
Chen, Yi-Cheng
Lin, Chih-Lang
Lin, Wey-Ran
Lai, Ming-Wei
author_facet Yeh, Chau-Ting
Liang, Kung-Hao
Chang, Ming-Ling
Hsu, Chao-Wei
Chen, Yi-Cheng
Lin, Chih-Lang
Lin, Wey-Ran
Lai, Ming-Wei
author_sort Yeh, Chau-Ting
collection PubMed
description We examined the characteristic changes of hepatitis B virus (HBV) in antiviral drug treatment–naive patients referred for pretreatment evaluation in Taiwan during 2008–2012. Over time, we observed substantial decreases in the prevalence of HBV e antigen (HBeAg) and increasing prevalence of the precore G1899A mutation and HBV-DNA levels in HBeAg-positive patients.
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spelling pubmed-54030582017-05-12 Phenotypic and Genotypic Shifts in Hepatitis B Virus in Treatment-Naive Patients, Taiwan, 2008–2012 Yeh, Chau-Ting Liang, Kung-Hao Chang, Ming-Ling Hsu, Chao-Wei Chen, Yi-Cheng Lin, Chih-Lang Lin, Wey-Ran Lai, Ming-Wei Emerg Infect Dis Dispatch We examined the characteristic changes of hepatitis B virus (HBV) in antiviral drug treatment–naive patients referred for pretreatment evaluation in Taiwan during 2008–2012. Over time, we observed substantial decreases in the prevalence of HBV e antigen (HBeAg) and increasing prevalence of the precore G1899A mutation and HBV-DNA levels in HBeAg-positive patients. Centers for Disease Control and Prevention 2017-05 /pmc/articles/PMC5403058/ /pubmed/28418295 http://dx.doi.org/10.3201/eid2305.161894 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Yeh, Chau-Ting
Liang, Kung-Hao
Chang, Ming-Ling
Hsu, Chao-Wei
Chen, Yi-Cheng
Lin, Chih-Lang
Lin, Wey-Ran
Lai, Ming-Wei
Phenotypic and Genotypic Shifts in Hepatitis B Virus in Treatment-Naive Patients, Taiwan, 2008–2012
title Phenotypic and Genotypic Shifts in Hepatitis B Virus in Treatment-Naive Patients, Taiwan, 2008–2012
title_full Phenotypic and Genotypic Shifts in Hepatitis B Virus in Treatment-Naive Patients, Taiwan, 2008–2012
title_fullStr Phenotypic and Genotypic Shifts in Hepatitis B Virus in Treatment-Naive Patients, Taiwan, 2008–2012
title_full_unstemmed Phenotypic and Genotypic Shifts in Hepatitis B Virus in Treatment-Naive Patients, Taiwan, 2008–2012
title_short Phenotypic and Genotypic Shifts in Hepatitis B Virus in Treatment-Naive Patients, Taiwan, 2008–2012
title_sort phenotypic and genotypic shifts in hepatitis b virus in treatment-naive patients, taiwan, 2008–2012
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403058/
https://www.ncbi.nlm.nih.gov/pubmed/28418295
http://dx.doi.org/10.3201/eid2305.161894
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