Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA

During 2016, eight Neisseria gonorrhoeae isolates from 7 patients in Hawaii were resistant to azithromycin; 5 had decreased in vitro susceptibility to ceftriaxone. Genomic analysis demonstrated a distinct phylogenetic clade when compared with local contemporary strains. Continued evolution and wides...

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Detalles Bibliográficos
Autores principales: Papp, John R., Abrams, A. Jeanine, Nash, Evelyn, Katz, Alan R., Kirkcaldy, Robert D., O’Connor, Norman P., O’Brien, Pamela S., Harauchi, Derek H., Maningas, Eloisa V., Soge, Olusegun O., Kersh, Ellen N., Komeya, Alan, Tomas, Juval E., Wasserman, Glenn M., Kunimoto, Gail Y., Trees, David L., Whelen, A. Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403062/
https://www.ncbi.nlm.nih.gov/pubmed/28418303
http://dx.doi.org/10.3201/eid2305.170088
Descripción
Sumario:During 2016, eight Neisseria gonorrhoeae isolates from 7 patients in Hawaii were resistant to azithromycin; 5 had decreased in vitro susceptibility to ceftriaxone. Genomic analysis demonstrated a distinct phylogenetic clade when compared with local contemporary strains. Continued evolution and widespread transmission of these strains might challenge the effectiveness of current therapeutic options.

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