Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA

During 2016, eight Neisseria gonorrhoeae isolates from 7 patients in Hawaii were resistant to azithromycin; 5 had decreased in vitro susceptibility to ceftriaxone. Genomic analysis demonstrated a distinct phylogenetic clade when compared with local contemporary strains. Continued evolution and wides...

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Autores principales: Papp, John R., Abrams, A. Jeanine, Nash, Evelyn, Katz, Alan R., Kirkcaldy, Robert D., O’Connor, Norman P., O’Brien, Pamela S., Harauchi, Derek H., Maningas, Eloisa V., Soge, Olusegun O., Kersh, Ellen N., Komeya, Alan, Tomas, Juval E., Wasserman, Glenn M., Kunimoto, Gail Y., Trees, David L., Whelen, A. Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403062/
https://www.ncbi.nlm.nih.gov/pubmed/28418303
http://dx.doi.org/10.3201/eid2305.170088
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author Papp, John R.
Abrams, A. Jeanine
Nash, Evelyn
Katz, Alan R.
Kirkcaldy, Robert D.
O’Connor, Norman P.
O’Brien, Pamela S.
Harauchi, Derek H.
Maningas, Eloisa V.
Soge, Olusegun O.
Kersh, Ellen N.
Komeya, Alan
Tomas, Juval E.
Wasserman, Glenn M.
Kunimoto, Gail Y.
Trees, David L.
Whelen, A. Christian
author_facet Papp, John R.
Abrams, A. Jeanine
Nash, Evelyn
Katz, Alan R.
Kirkcaldy, Robert D.
O’Connor, Norman P.
O’Brien, Pamela S.
Harauchi, Derek H.
Maningas, Eloisa V.
Soge, Olusegun O.
Kersh, Ellen N.
Komeya, Alan
Tomas, Juval E.
Wasserman, Glenn M.
Kunimoto, Gail Y.
Trees, David L.
Whelen, A. Christian
author_sort Papp, John R.
collection PubMed
description During 2016, eight Neisseria gonorrhoeae isolates from 7 patients in Hawaii were resistant to azithromycin; 5 had decreased in vitro susceptibility to ceftriaxone. Genomic analysis demonstrated a distinct phylogenetic clade when compared with local contemporary strains. Continued evolution and widespread transmission of these strains might challenge the effectiveness of current therapeutic options.
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spelling pubmed-54030622017-05-12 Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA Papp, John R. Abrams, A. Jeanine Nash, Evelyn Katz, Alan R. Kirkcaldy, Robert D. O’Connor, Norman P. O’Brien, Pamela S. Harauchi, Derek H. Maningas, Eloisa V. Soge, Olusegun O. Kersh, Ellen N. Komeya, Alan Tomas, Juval E. Wasserman, Glenn M. Kunimoto, Gail Y. Trees, David L. Whelen, A. Christian Emerg Infect Dis Dispatch During 2016, eight Neisseria gonorrhoeae isolates from 7 patients in Hawaii were resistant to azithromycin; 5 had decreased in vitro susceptibility to ceftriaxone. Genomic analysis demonstrated a distinct phylogenetic clade when compared with local contemporary strains. Continued evolution and widespread transmission of these strains might challenge the effectiveness of current therapeutic options. Centers for Disease Control and Prevention 2017-05 /pmc/articles/PMC5403062/ /pubmed/28418303 http://dx.doi.org/10.3201/eid2305.170088 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Papp, John R.
Abrams, A. Jeanine
Nash, Evelyn
Katz, Alan R.
Kirkcaldy, Robert D.
O’Connor, Norman P.
O’Brien, Pamela S.
Harauchi, Derek H.
Maningas, Eloisa V.
Soge, Olusegun O.
Kersh, Ellen N.
Komeya, Alan
Tomas, Juval E.
Wasserman, Glenn M.
Kunimoto, Gail Y.
Trees, David L.
Whelen, A. Christian
Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA
title Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA
title_full Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA
title_fullStr Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA
title_full_unstemmed Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA
title_short Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA
title_sort azithromycin resistance and decreased ceftriaxone susceptibility in neisseria gonorrhoeae, hawaii, usa
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403062/
https://www.ncbi.nlm.nih.gov/pubmed/28418303
http://dx.doi.org/10.3201/eid2305.170088
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