Zika Virus Infection and Prolonged Viremia in Whole-Blood Specimens

We tested whole-blood and plasma samples from immunocompetent patients who had had benign Zika virus infections and found that Zika virus RNA persisted in whole blood substantially longer than in plasma. This finding may have implications for diagnosis of acute symptomatic and asymptomatic infection...

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Autores principales: Mansuy, Jean Michel, Mengelle, Catherine, Pasquier, Christophe, Chapuy-Regaud, Sabine, Delobel, Pierre, Martin-Blondel, Guillaume, Izopet, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403064/
https://www.ncbi.nlm.nih.gov/pubmed/28257281
http://dx.doi.org/10.3201/eid2305.161631
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author Mansuy, Jean Michel
Mengelle, Catherine
Pasquier, Christophe
Chapuy-Regaud, Sabine
Delobel, Pierre
Martin-Blondel, Guillaume
Izopet, Jacques
author_facet Mansuy, Jean Michel
Mengelle, Catherine
Pasquier, Christophe
Chapuy-Regaud, Sabine
Delobel, Pierre
Martin-Blondel, Guillaume
Izopet, Jacques
author_sort Mansuy, Jean Michel
collection PubMed
description We tested whole-blood and plasma samples from immunocompetent patients who had had benign Zika virus infections and found that Zika virus RNA persisted in whole blood substantially longer than in plasma. This finding may have implications for diagnosis of acute symptomatic and asymptomatic infections and for testing of blood donations.
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spelling pubmed-54030642017-05-12 Zika Virus Infection and Prolonged Viremia in Whole-Blood Specimens Mansuy, Jean Michel Mengelle, Catherine Pasquier, Christophe Chapuy-Regaud, Sabine Delobel, Pierre Martin-Blondel, Guillaume Izopet, Jacques Emerg Infect Dis Research Letter We tested whole-blood and plasma samples from immunocompetent patients who had had benign Zika virus infections and found that Zika virus RNA persisted in whole blood substantially longer than in plasma. This finding may have implications for diagnosis of acute symptomatic and asymptomatic infections and for testing of blood donations. Centers for Disease Control and Prevention 2017-05 /pmc/articles/PMC5403064/ /pubmed/28257281 http://dx.doi.org/10.3201/eid2305.161631 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Mansuy, Jean Michel
Mengelle, Catherine
Pasquier, Christophe
Chapuy-Regaud, Sabine
Delobel, Pierre
Martin-Blondel, Guillaume
Izopet, Jacques
Zika Virus Infection and Prolonged Viremia in Whole-Blood Specimens
title Zika Virus Infection and Prolonged Viremia in Whole-Blood Specimens
title_full Zika Virus Infection and Prolonged Viremia in Whole-Blood Specimens
title_fullStr Zika Virus Infection and Prolonged Viremia in Whole-Blood Specimens
title_full_unstemmed Zika Virus Infection and Prolonged Viremia in Whole-Blood Specimens
title_short Zika Virus Infection and Prolonged Viremia in Whole-Blood Specimens
title_sort zika virus infection and prolonged viremia in whole-blood specimens
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403064/
https://www.ncbi.nlm.nih.gov/pubmed/28257281
http://dx.doi.org/10.3201/eid2305.161631
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