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Prominin-1 Is a Novel Regulator of Autophagy in the Human Retinal Pigment Epithelium

PURPOSE: Prominin-1 (Prom1) is a transmembrane glycoprotein, which is expressed in stem cell lineages, and has recently been implicated in cancer stem cell survival. Mutations in the Prom1 gene have been shown to disrupt photoreceptor disk morphogenesis and cause an autosomal dominant form of Starga...

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Detalles Bibliográficos
Autores principales:	Bhattacharya, Sujoy, Yin, Jinggang, Winborn, Christina S., Zhang, Qiuhua, Yue, Junming, Chaum, Edward
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2017
Materias:	Biochemistry and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403116/ https://www.ncbi.nlm.nih.gov/pubmed/28437526 http://dx.doi.org/10.1167/iovs.16-21162

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