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NVP-AUY922, a novel HSP90 inhibitor, inhibits the progression of malignant pheochromocytoma in vitro and in vivo

PURPOSE: Malignant pheochromocytoma (PCC) is a rare tumor with a very poor prognosis and no effective treatments. The aim of this study was to assess the efficacy of a novel second-generation synthetic heat-shock protein 90 (HSP90) inhibitor, NVP-AUY922, to treat malignant PCC in vitro and in vivo....

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Detalles Bibliográficos
Autores principales:	Lian, Jianpo, Lin, Dengqiang, Xie, Xing, Xu, Yunze, Xu, Lieyu, Meng, Li, Zhu, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403128/ https://www.ncbi.nlm.nih.gov/pubmed/28458565 http://dx.doi.org/10.2147/OTT.S130236

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