Cargando…
Sirtuins and DNA damage repair: SIRT7 comes to play
Aging is characterized by a cumulative loss of genome integrity, which involves chromatin reorganization, transcriptional dysregulation and the accumulation of DNA damage. Sirtuins participate in the protection against these aging processes by promoting genome homeostasis in response to cellular str...
Autores principales: | Vazquez, Berta N., Thackray, Joshua K., Serrano, Lourdes |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403131/ https://www.ncbi.nlm.nih.gov/pubmed/28406750 http://dx.doi.org/10.1080/19491034.2016.1264552 |
Ejemplares similares
-
Sirt7 inhibits Sirt1-mediated activation of Suv39h1
por: Kumari, Poonam, et al.
Publicado: (2018) -
From dynamic chromatin architecture to DNA damage repair and back
por: Fabre, Emmanuelle, et al.
Publicado: (2018) -
DNA double strand break repair pathway choice: a chromatin based decision?
por: Clouaire, T, et al.
Publicado: (2015) -
Extra View: Sirt1 Acts As A Gatekeeper Of Replication Initiation To Preserve Genomic Stability.
por: Utani, Koichi, et al.
Publicado: (2018) -
The BRCA1 Ubiquitin ligase function sets a new trend for remodelling in DNA repair
por: Densham, Ruth M., et al.
Publicado: (2016)