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MARCKS phosphorylation is modulated by a peptide mimetic of MARCKS effector domain leading to increased radiation sensitivity in lung cancer cell lines
Lung cancer is the leading cause of cancer-associated mortality in the United States. Kinase hyperactivation is a known mechanism of tumorigenesis. The phosphorylation status of the plasma membrane-associated protein myristoylated alanine rich C-kinase substrate (MARCKS) effector domain (ED) was pre...
Autores principales: | Rohrbach, Timothy D., Jones, Robert B., Hicks, Patricia H., Weaver, Alice N., Cooper, Tiffiny S., Eustace, Nicholas J., Yang, Eddy S., Jarboe, John S., Anderson, Joshua C., Willey, Christopher D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403188/ https://www.ncbi.nlm.nih.gov/pubmed/28454237 http://dx.doi.org/10.3892/ol.2016.5550 |
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