B1, a novel HDAC inhibitor, induces apoptosis through the regulation of STAT3 and NF-κB

We previously demonstrated that B1 induced significant cytotoxic effects, cell cycle G1 arrest and apoptosis in human lung cancer A549 cells through the inhibition of DNA topoisomerase II activity. In the present study, we focused on the histone deacetylase (HDAC) modulation of B1 in A549 cells. HDA...

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Detalles Bibliográficos
Autores principales: Cheng, Meng-Hsuan, Wong, Yun-Hong, Chang, Chia-Ming, Yang, Chun-Chien, Chen, Shih-Hua, Yuan, Chun-Lung, Kuo, Hsiao-Mei, Yang, Chun-Yuh, Chiu, Hui-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403210/
https://www.ncbi.nlm.nih.gov/pubmed/28393178
http://dx.doi.org/10.3892/ijmm.2017.2946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403210/
https://www.ncbi.nlm.nih.gov/pubmed/28393178
http://dx.doi.org/10.3892/ijmm.2017.2946

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