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Antitumor effects of a dual-specific lentiviral vector carrying the Escherichia coli purine nucleoside phosphorylase gene

The Escherichia coli purine nucleoside phosphorylase/Fludarabine phosphate (ePNP/Fludara) suicide system has several drawbacks, such as side-effects and the low efficiency of ePNP expression. In this study, we evaluated the antitumor effects of the dual-specific 8HSEs-hTERTp-ePNP/Fludara suicide sys...

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Detalles Bibliográficos
Autores principales: Wang, Xiaolong, Sun, Lei, Sun, Xuejun, Yu, Junhui, Wang, Kai, Wu, Yunhua, Gao, Qi, Zheng, Jianbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403222/
https://www.ncbi.nlm.nih.gov/pubmed/28393254
http://dx.doi.org/10.3892/ijo.2017.3949