Cargando…

Expression of inositol-requiring enzyme 1β is downregulated in colorectal cancer

The endoplasmic reticulum stress inositol-requiring enzyme (IRE) 1α/X-box binding protein (XBP) 1 signaling pathway is involved in the tumorigenesis of breast and prostate cancer. Mucin 2 (MUC2) protects colon tissues from the formation of tumors. In human colorectal cancer (CRC) the role of IRE1α,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Yalin, Zhou, Yunfeng, Zheng, Yufeng, Guo, Hong, Gao, Lei, Chen, Pan, Feng, Dandan, Qi, Ran, Li, Xiaozhen, Chang, Yongchao, Chu, Fong-Fong, Gao, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403352/ https://www.ncbi.nlm.nih.gov/pubmed/28454221 http://dx.doi.org/10.3892/ol.2017.5590

Ejemplares similares

Serotonin-Exacerbated DSS-Induced Colitis Is Associated with Increase in MMP-3 and MMP-9 Expression in the Mouse Colon
por: Chen, Menglu, et al.
Publicado: (2016)

The Gastric Mucosa from Patients Infected with CagA+ or VacA+ Helicobacter pylori Has a Lower Level of Dual Oxidase-2 Expression than Uninfected or Infected with CagA−/VacA− H. pylori
por: Li, Hongqian, et al.
Publicado: (2016)

Potent and Selective Inhibitors of the Inositol-requiring Enzyme 1 Endoribonuclease
por: Volkmann, Kori, et al.
Publicado: (2011)

Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase Domain
por: Carlesso, Antonio, et al.
Publicado: (2018)

DUOX2 Expression Is Increased in Barrett Esophagus and Cancerous Tissues of Stomach and Colon
por: Qi, Ran, et al.
Publicado: (2016)

Inositol Requiring Enzyme (IRE), a multiplayer in sensing endoplasmic reticulum stress
por: Zhou, Zhixin, et al.
Publicado: (2022)

Combination of Inositol Hexaphosphate and Inositol Inhibits Liver Metastasis of Colorectal Cancer in Mice Through the Wnt/β-Catenin Pathway
por: Liu, Xiaohan, et al.
Publicado: (2020)

Inositol hexakisphosphate is required for Integrator function
por: Lin, Min-Han, et al.
Publicado: (2022)

Multiple autophosphorylations significantly enhance the endoribonuclease activity of human inositol requiring enzyme 1α
por: Itzhak, Daniel, et al.
Publicado: (2014)

Inositol-Requiring Enzyme 1 Facilitates Diabetic Wound Healing Through Modulating MicroRNAs
por: Wang, Jie-Mei, et al.
Publicado: (2017)

Deletion of inositol-requiring enzyme-1α in podocytes disrupts glomerular capillary integrity and autophagy
por: Kaufman, Daniel Robert, et al.
Publicado: (2017)

Inositol Pyrophosphate Synthesis by Inositol Hexakisphosphate Kinase 1 Is Required for Homologous Recombination Repair
por: Jadav, Rathan S., et al.
Publicado: (2013)

Inositol Hexaphosphate and Inositol Inhibit Colorectal Cancer Metastasis to the Liver in BALB/c Mice
por: Fu, Min, et al.
Publicado: (2016)

Inositol Monophosphatase: A Bifunctional Enzyme in Mycobacterium smegmatis
por: Goswami, Rajendra, et al.
Publicado: (2018)

Targeting the Inositol Pyrophosphate Biosynthetic Enzymes in Metabolic Diseases
por: Mukherjee, Sandip, et al.
Publicado: (2020)

Opposite Roles of RNase and Kinase Activities of Inositol-Requiring Enzyme 1 (IRE1) on HSV-1 Replication
por: Su, Airong, et al.
Publicado: (2017)

Sinomenine alleviates diabetic peripheral neuropathic pain through inhibition of the inositol‐requiring enzyme 1 alpha–X‐box binding protein 1 pathway by downregulating prostaglandin‐endoperoxide synthase 2
por: Chen, Ji, et al.
Publicado: (2023)

Metabolomics analyses of cancer tissue from patients with colorectal cancer
por: Kang, Chunbo, et al.
Publicado: (2023)

The effect of D-chiro-inositol on renal protection in diabetic mice
por: Fan, Chunxue, et al.
Publicado: (2022)

Primate lentiviruses require Inositol hexakisphosphate (IP6) or inositol pentakisphosphate (IP5) for the production of viral particles
por: Ricana, Clifton L., et al.
Publicado: (2020)

Binding to an Unusual Inactive Kinase Conformation by Highly Selective Inhibitors of Inositol-Requiring Enzyme 1α Kinase-Endoribonuclease
por: Colombano, Giampiero, et al.
Publicado: (2019)

The ER stress sensor inositol-requiring enzyme 1α in Kupffer cells promotes hepatic ischemia-reperfusion injury
por: Cai, Jie, et al.
Publicado: (2021)

Serum pepsinogen II levels are doubled with Helicobacter pylori infection in an asymptomatic population of 40,383 Chinese subjects
por: Yu, Hong, et al.
Publicado: (2021)

Inositol-Requiring Enzyme 1 Alpha Endoribonuclease Specific Inhibitor STF-083010 Alleviates Carbon Tetrachloride Induced Liver Injury and Liver Fibrosis in Mice
por: Chen, Qian-Qian, et al.
Publicado: (2018)

Lipidomics Analysis of Outer Membrane Vesicles and Elucidation of the Inositol Phosphoceramide Biosynthetic Pathway in Bacteroides thetaiotaomicron
por: Sartorio, Mariana G., et al.
Publicado: (2022)

The Endoplasmic Reticulum Stress Sensor Inositol-Requiring Enzyme 1α Augments Bacterial Killing through Sustained Oxidant Production
por: Abuaita, Basel H., et al.
Publicado: (2015)

Knockout of inositol-requiring enzyme 1α in pro-opiomelanocortin neurons decreases fat mass via increasing energy expenditure
por: Xiao, Yuzhong, et al.
Publicado: (2016)

Increased NOX1 and DUOX2 expression in the colonic mucosa of patients with chronic functional constipation
por: Wei, Xiuqin, et al.
Publicado: (2022)

Multibody cofactor and substrate molecular recognition in the myo-inositol monophosphatase enzyme
por: Ferruz, Noelia, et al.
Publicado: (2016)

Dissecting the activation of insulin degrading enzyme by inositol pyrophosphates and their bisphosphonate analogs
por: Hostachy, Sarah, et al.
Publicado: (2021)

Inositol-Requiring Enzyme 1-Mediated Downregulation of MicroRNA (miR)-146a and miR-155 in Primary Dermal Fibroblasts across Three TNFRSF1A Mutations Results in Hyperresponsiveness to Lipopolysaccharide
por: Harrison, Stephanie R., et al.
Publicado: (2018)

Role of Inositols and Inositol Phosphates in Energy Metabolism
por: Chatree, Saimai, et al.
Publicado: (2020)

Myo-inositol reduces β-catenin activation in colitis
por: Bradford, Emily M, et al.
Publicado: (2017)

Inositol-requiring enzyme 1α/X-box protein 1 pathway expression is impaired in pediatric cholestatic liver disease explants
por: Kriegermeier, Alyssa, et al.
Publicado: (2022)

MCK1 is a novel regulator of myo-inositol phosphate synthase (MIPS) that is required for inhibition of inositol synthesis by the mood stabilizer valproate
por: Yu, Wenxi, et al.
Publicado: (2017)

Direct Ionic Regulation of the Activity of Myo-Inositol Biosynthesis Enzymes in Mozambique Tilapia
por: Villarreal, Fernando D., et al.
Publicado: (2015)

Efficient Multi-Enzymes Immobilized on Porous Microspheres for Producing Inositol From Starch
por: Han, Pingping, et al.
Publicado: (2020)

Application of Inositol Hexaphosphate and Inositol in Dental Medicine: An Overview
por: Druzijanic, Ana, et al.
Publicado: (2023)

Nicotinic acetylcholine receptor signaling regulates inositol‐requiring enzyme 1α activation to protect β‐cells against terminal unfolded protein response under irremediable endoplasmic reticulum stress
por: Ishibashi, Tatsuya, et al.
Publicado: (2020)

QM/MM Well-Tempered Metadynamics Study of the Mechanism of XBP1 mRNA Cleavage by Inositol Requiring Enzyme 1α RNase
por: Mahdizadeh, Sayyed Jalil, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_atp47esn5um4ps8le36jo9bd2r