Cargando…

WIF-1 gene inhibition and Wnt signal transduction pathway activation in NSCLC tumorigenesis

The aim of the present study is to explore the differential expression of key molecules associated with Wnt signaling in both clinical non-small cell lung cancer (NSCLC) tissue and adjacent normal lung tissue, and to discuss the tumorigenic role of the activation of Wnt signaling pathways in NSCLC....

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Qiong, Zhao, Hui, Yang, Bingjun, Li, Li, Shi, Qiulan, Jiang, Chunyang, Liu, Huibin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403432/ https://www.ncbi.nlm.nih.gov/pubmed/28454231 http://dx.doi.org/10.3892/ol.2017.5566

Ejemplares similares

Indirubin inhibits Wnt/β-catenin signal pathway via promoter demethylation of WIF-1
por: Liu, Shou Gang, et al.
Publicado: (2020)

m(6)A demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling
por: Tang, Bo, et al.
Publicado: (2020)

An Eye on the Wnt Inhibitory Factor Wif1
por: Poggi, Lucia, et al.
Publicado: (2018)

Loss of CLDN5 in podocytes deregulates WIF1 to activate WNT signaling and contributes to kidney disease
por: Sun, Hui, et al.
Publicado: (2022)

Wnt/β-catenin signal transduction pathway in prostate cancer and associated drug resistance
por: Wang, Chunyang, et al.
Publicado: (2021)

The negative regulators of Wnt pathway—DACH1, DKK1, and WIF1 are methylated in oral and oropharyngeal cancer and WIF1 methylation predicts shorter survival
por: Paluszczak, Jarosław, et al.
Publicado: (2014)

A long non-coding RNA, HOTAIR, promotes cartilage degradation in osteoarthritis by inhibiting WIF-1 expression and activating Wnt pathway
por: Yang, Yang, et al.
Publicado: (2020)

Gossypol Promotes Wnt/β-Catenin Signaling through WIF1 in Ovariectomy-Induced Osteoporosis
por: Liang, Jinqian, et al.
Publicado: (2019)

The Role of Glypicans in Wnt Inhibitory Factor-1 Activity and the Structural Basis of Wif1's Effects on Wnt and Hedgehog Signaling
por: Avanesov, Andrei, et al.
Publicado: (2012)

Clinicopathological significance of WIF1 hypermethylation in NSCLC, a meta-analysis and literature review
por: Guo, Hao, et al.
Publicado: (2016)

Cellular retinol binding protein-1 inhibits cancer stemness via upregulating WIF1 to suppress Wnt/β-catenin pathway in hepatocellular carcinoma
por: Liu, Xiangye, et al.
Publicado: (2021)

Wif1 Mediates Coordination of Bone Morphogenetic Protein and Wnt Signaling in Neural and Glioma Stem Cells
por: Xu, Congdi, et al.
Publicado: (2022)

Wnt signal transduction pathway and apoptosis: a review
por: Pećina-Šlaus, Nives
Publicado: (2010)

Wnt signal transduction pathways: modules, development and evolution
por: Nayak, Losiana, et al.
Publicado: (2016)

Extracellular activation of Wnt signaling through epigenetic dysregulation of Wnt inhibitory factor-1 (Wif-1) is associated with pathogenesis of adrenocortical tumor
por: Mitsui, Yozo, et al.
Publicado: (2014)

Effects of propofol on colon cancer metastasis through STAT3/HOTAIR axis by activating WIF‐1 and suppressing Wnt pathway
por: Zhang, Yun‐Fei, et al.
Publicado: (2020)

Epigenetic regulation of human WIF1 and DNA methylation situation of WIF1 and GSTM5 in urothelial carcinoma
por: Shen, Cheng-Huang, et al.
Publicado: (2023)

20(S)- Protopanaxadiol suppresses hepatic stellate cell activation via WIF1 demethylation-mediated inactivation of the Wnt/β-catenin pathway
por: Li, Chunxue, et al.
Publicado: (2023)

Dysregulation of Wnt inhibitory factor 1 (Wif1) expression resulted in aberrant Wnt-β-catenin signaling and cell death of the cloaca endoderm, and anorectal malformations
por: Ng, R C-L, et al.
Publicado: (2014)

Promoter Hypermethylation of Wnt/β-catenin Signaling Pathway Inhibitor WIF-1 Gene and its Association with MTHFR C677T Polymorphism in Patients with Colorectal Cancer
por: Jalilvand, Ahmad, et al.
Publicado: (2020)

Wnt inhibitory factor 1 (WIF1) methylation and its association with clinical prognosis in patients with chondrosarcoma
por: Liu, Pei, et al.
Publicado: (2017)

Local anesthetic thoracoscopy for the diagnosis of metastatic pleural melanoma originated from oral malignant melanoma: case report and comments
por: Yang, Bingjun, et al.
Publicado: (2015)

MiR181-5p promotes pathogenic angiogenesis of hepatopulmonary syndrome by negatively regulating Wnt inhibitor Wif1
por: Li, Dan, et al.
Publicado: (2023)

Knockdown of SNORA47 Inhibits the Tumorigenesis of NSCLC via Mediation of PI3K/Akt Signaling Pathway
por: Yu, Huiqing, et al.
Publicado: (2021)

Cell-autonomous signal transduction in the Xenopus egg Wnt/β-catenin pathway
por: Motomura, Eriko, et al.
Publicado: (2014)

Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their Crosstalks
por: Zhang, Jingyu, et al.
Publicado: (2016)

The Wnt signaling pathway in tumorigenesis, pharmacological targets, and drug development for cancer therapy
por: Wang, Zhuo, et al.
Publicado: (2021)

Role of bacterial infection in the epigenetic regulation of Wnt antagonist WIF1 by PRC2 protein EZH2
por: Roy, Badal C., et al.
Publicado: (2014)

ZNF671 Inhibits the Proliferation and Metastasis of NSCLC via the Wnt/β-Catenin Pathway
por: Zhan, Wei, et al.
Publicado: (2020)

CNSC-02. INVESTIGATING THE ROLE OF THE WNT SIGNALING TRANSDUCTION PATHWAY IN GLIOMA BLOOD-BRAIN-BARRIER INTEGRITY
por: Tang, Kayen, et al.
Publicado: (2023)

Clinical relevance of genetic polymorphisms in WNT signaling pathway (SFRP1, WNT3A, CTNNB1, WIF-1, DKK-1, LRP5, LRP6) on pulmonary tuberculosis in a Chinese population
por: Huang, Qian, et al.
Publicado: (2022)

Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity
por: Schlessinger, Karni, et al.
Publicado: (2007)

OTX1 promotes tumorigenesis and progression of cervical cancer by regulating the Wnt signaling pathway
por: Zhou, Limin, et al.
Publicado: (2022)

PRC1 contributes to tumorigenesis of lung adenocarcinoma in association with the Wnt/β-catenin signaling pathway
por: Zhan, Ping, et al.
Publicado: (2017)

Reorganisation of Wnt-response pathways in colorectal tumorigenesis
por: Caldwell, G M, et al.
Publicado: (2008)

Overexpression of CD300A inhibits progression of NSCLC through downregulating Wnt/β-catenin pathway
por: Tang, Ze, et al.
Publicado: (2018)

RBM5 inhibits tumorigenesis of gliomas through inhibition of Wnt/β-catenin signaling and induction of apoptosis
por: Jiang, Yuanpei, et al.
Publicado: (2017)

WIF1 causes dysfunction of heart in transgenic mice
por: Lu, Dan, et al.
Publicado: (2013)

PRMT5 acts as a tumor suppressor by inhibiting Wnt/β-catenin signaling in murine gastric tumorigenesis
por: Tang, Yuling, et al.
Publicado: (2022)

Delivery of Wnt inhibitor WIF1 via engineered polymeric microspheres promotes nerve regeneration after sciatic nerve crush
por: Zhang, Na, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9tbiinblcr3pe8v1pa12iu8g8a