A multi-shRNA vector enhances the silencing efficiency of exogenous and endogenous genes in human cells

RNA interference (RNAi) is a powerful technology for suppressing gene function. In most studies, small interfering RNAs (siRNAs) consist of one short hairpin RNA (shRNA) and, therefore, are often unable to achieve loss-of-function of their target genes. In the current study, an RNAi vector containin...

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Detalles Bibliográficos
Autores principales: Weng, Yanjie, Shi, Ying, Xia, Xi, Zhou, Wenjuan, Wang, Hongyan, Wang, Changyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403481/
https://www.ncbi.nlm.nih.gov/pubmed/28454290
http://dx.doi.org/10.3892/ol.2017.5672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403481/
https://www.ncbi.nlm.nih.gov/pubmed/28454290
http://dx.doi.org/10.3892/ol.2017.5672

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