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Atorvastatin attenuates plaque vulnerability by downregulation of EMMPRIN expression via COX-2/PGE2 pathway

Extracellular matrix metalloproteinase inducer (EMMPRIN) reportedly has a key regulatory role in matrix metalloproteinase (MMP) activities and the progression of atherosclerosis. Statins, which are anti-atherosclerotic pharmacological agents, are widely applied in clinical settings. The aim of the p...

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Detalles Bibliográficos
Autores principales: Liang, Xing, Yang, Li-Xia, Guo, Ruiwei, Shi, Yankun, Hou, Xianhua, Yang, Zhihua, Zhou, Xiaobin, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403495/
https://www.ncbi.nlm.nih.gov/pubmed/28450907
http://dx.doi.org/10.3892/etm.2017.4062