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SIRT1 is required for mitochondrial biogenesis reprogramming in hypoxic human pulmonary arteriolar smooth muscle cells

Although recent studies have reported that mitochondria are putative oxygen sensors underlying hypoxic pulmonary vasoconstriction, little is known concerning the sirtuin 1 (SIRT1)-mediated mitochondrial biogenesis regulatory program in pulmonary arteriolar smooth muscle cells (PASMCs) during hypoxia...

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Detalles Bibliográficos
Autores principales:	Li, Pengyun, Liu, Yan, Burns, Nana, Zhao, Ke-Seng, Song, Rui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403509/ https://www.ncbi.nlm.nih.gov/pubmed/28339017 http://dx.doi.org/10.3892/ijmm.2017.2932

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