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Role of autophagy in the progression of osteoarthritis: The autophagy inhibitor, 3-methyladenine, aggravates the severity of experimental osteoarthritis

Accumulating evidence suggests that autophagy is closely related to the pathogenesis of osteoarthritis (OA). The aim of this study was to determine the changes in autophagy during the progression of OA and to elucidate the specific role of autophagy in OA. For this purpose, a cellular model of OA wa...

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Detalles Bibliográficos
Autores principales: Cheng, Ni-Tao, Meng, Hai, Ma, Li-Feng, Zhang, Liang, Yu, Hao-Miao, Wang, Zhen-Zhong, Guo, Ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403511/
https://www.ncbi.nlm.nih.gov/pubmed/28339018
http://dx.doi.org/10.3892/ijmm.2017.2934

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