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Smad3 mutant mice develop colon cancer with overexpression of COX-2

Colon cancer is the second most common cause of cancer-associated mortality in human populations. The aim of the present study was to identify the role of cyclooxygenase-2 (COX-2) in Smad3 mutant mice, which are known to develop colon cancer. Homozygous Smad3 (−/−) mutant mice were generated from in...

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Detalles Bibliográficos
Autores principales:	Zhu, Yu-Ping, Liu, Zhuo, Fu, Zhi-Xuan, Li, De-Chuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403702/ https://www.ncbi.nlm.nih.gov/pubmed/28454287 http://dx.doi.org/10.3892/ol.2017.5639

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