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Surgical treatment of solid hemangioblastomas of the posterior fossa: A report of 28 cases
This study evaluated the clinical features, treatment strategies and outcomes of solid hemangioblastomas in 28 patients diagnosed with hypervascular lesions in the posterior fossa. Preoperative embolization of the feeding arteries had limited effects, with only 7 patients benefitting from it for the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403715/ https://www.ncbi.nlm.nih.gov/pubmed/28454223 http://dx.doi.org/10.3892/ol.2016.5531 |
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author | Cui, Hua Zou, Jian Bao, Ying-Hui Wang, Ming-Sheng Wang, Yong |
author_facet | Cui, Hua Zou, Jian Bao, Ying-Hui Wang, Ming-Sheng Wang, Yong |
author_sort | Cui, Hua |
collection | PubMed |
description | This study evaluated the clinical features, treatment strategies and outcomes of solid hemangioblastomas in 28 patients diagnosed with hypervascular lesions in the posterior fossa. Preoperative embolization of the feeding arteries had limited effects, with only 7 patients benefitting from it for the reduction of intraoperative hemorrhage. The tumor was completely removed in all patients, and 22 patients had a full recovery, while 6 patients, all of whom had van Hippel Lindau disease, developed recurrences. The present study demonstrated that meticulous en bloc surgical resection was the optimal treatment for solid hemangioblastomas of the posterior fossa. For large tumors, preoperative embolization was critical for preventing postoperative morbidity. Given the improvements in microsurgical techniques and the understanding of the tumor vascular pattern, total tumor removal associated with a low mortality rate could be achieved. |
format | Online Article Text |
id | pubmed-5403715 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-54037152017-04-27 Surgical treatment of solid hemangioblastomas of the posterior fossa: A report of 28 cases Cui, Hua Zou, Jian Bao, Ying-Hui Wang, Ming-Sheng Wang, Yong Oncol Lett Articles This study evaluated the clinical features, treatment strategies and outcomes of solid hemangioblastomas in 28 patients diagnosed with hypervascular lesions in the posterior fossa. Preoperative embolization of the feeding arteries had limited effects, with only 7 patients benefitting from it for the reduction of intraoperative hemorrhage. The tumor was completely removed in all patients, and 22 patients had a full recovery, while 6 patients, all of whom had van Hippel Lindau disease, developed recurrences. The present study demonstrated that meticulous en bloc surgical resection was the optimal treatment for solid hemangioblastomas of the posterior fossa. For large tumors, preoperative embolization was critical for preventing postoperative morbidity. Given the improvements in microsurgical techniques and the understanding of the tumor vascular pattern, total tumor removal associated with a low mortality rate could be achieved. D.A. Spandidos 2017-03 2016-12-23 /pmc/articles/PMC5403715/ /pubmed/28454223 http://dx.doi.org/10.3892/ol.2016.5531 Text en Copyright: © Cui et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Articles Cui, Hua Zou, Jian Bao, Ying-Hui Wang, Ming-Sheng Wang, Yong Surgical treatment of solid hemangioblastomas of the posterior fossa: A report of 28 cases |
title | Surgical treatment of solid hemangioblastomas of the posterior fossa: A report of 28 cases |
title_full | Surgical treatment of solid hemangioblastomas of the posterior fossa: A report of 28 cases |
title_fullStr | Surgical treatment of solid hemangioblastomas of the posterior fossa: A report of 28 cases |
title_full_unstemmed | Surgical treatment of solid hemangioblastomas of the posterior fossa: A report of 28 cases |
title_short | Surgical treatment of solid hemangioblastomas of the posterior fossa: A report of 28 cases |
title_sort | surgical treatment of solid hemangioblastomas of the posterior fossa: a report of 28 cases |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403715/ https://www.ncbi.nlm.nih.gov/pubmed/28454223 http://dx.doi.org/10.3892/ol.2016.5531 |
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