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From PK/PD to QSP: Understanding the Dynamic Effect of Cholesterol-Lowering Drugs on Atherosclerosis Progression and Stratified Medicine

Current computational and mathematical tools are demonstrating the high value of using systems modeling approaches (e.g. Quantitative Systems Pharmacology) to understand the effect of a given compound on the biological and physiological mechanisms related to a specific disease. This review provides...

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Detalles Bibliográficos
Autores principales:	Pichardo-Almarza, Cesar, Diaz-Zuccarini, Vanessa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403958/ https://www.ncbi.nlm.nih.gov/pubmed/27592718 http://dx.doi.org/10.2174/1381612822666160905095402

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