Cargando…
Polypharmacology in Precision Oncology: Current Applications and Future Prospects
Over the past decade, a more comprehensive, large-scale approach to studying cancer genetics and biology has revealed the challenges of tumor heterogeneity, adaption, evolution and drug resistance, while systems-based pharmacology and chemical biology strategies have uncovered a much more complex in...
Autores principales: | Antolin, Albert A., Workman, Paul, Mestres, Jordi, Al-Lazikani, Bissan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403974/ https://www.ncbi.nlm.nih.gov/pubmed/27669965 http://dx.doi.org/10.2174/1381612822666160923115828 |
Ejemplares similares
-
Evolution of kinase polypharmacology across HSP90 drug discovery
por: Antolin, Albert A., et al.
Publicado: (2021) -
The kinase polypharmacology landscape of clinical PARP inhibitors
por: Antolin, Albert A., et al.
Publicado: (2020) -
Objective, Quantitative, Data-Driven Assessment of Chemical Probes
por: Antolin, Albert A., et al.
Publicado: (2018) -
Blocking the survival of the nastiest by HSP90 inhibition
por: Workman, Paul, et al.
Publicado: (2016) -
SiGNet: A signaling network data simulator to enable signaling network inference
por: Coker, Elizabeth A., et al.
Publicado: (2017)