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Acid sphingomyelinase deficiency in Western diet-fed mice protects against adipocyte hypertrophy and diet-induced liver steatosis

OBJECTIVE: Alterations in sphingolipid and ceramide metabolism have been associated with various diseases, including nonalcoholic fatty liver disease (NAFLD). Acid sphingomyelinase (ASM) converts the membrane lipid sphingomyelin to ceramide, thereby affecting membrane composition and domain formatio...

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Detalles Bibliográficos
Autores principales:	Sydor, Svenja, Sowa, Jan-Peter, Megger, Dominik A., Schlattjan, Martin, Jafoui, Sami, Wingerter, Lena, Carpinteiro, Alexander, Baba, Hideo A., Bechmann, Lars P., Sitek, Barbara, Gerken, Guido, Gulbins, Erich, Canbay, Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404101/ https://www.ncbi.nlm.nih.gov/pubmed/28462076 http://dx.doi.org/10.1016/j.molmet.2017.03.002

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