Cargando…

A growth‐ and bioluminescence‐based bioreporter for the in vivo detection of novel biocatalysts

The use of bioreporters in high‐throughput screening for small molecules is generally laborious and/or expensive. The technology can be simplified by coupling the generation of a desired compound to cell survival, causing only positive cells to stay in the pool of generated variants. Here, a dual se...

Descripción completa

Detalles Bibliográficos
Autores principales: van Rossum, Teunke, Muras, Aleksandra, Baur, Marco J.J., Creutzburg, Sjoerd C.A., van der Oost, John, Kengen, Servé W.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404197/
https://www.ncbi.nlm.nih.gov/pubmed/28393499
http://dx.doi.org/10.1111/1751-7915.12612