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A growth‐ and bioluminescence‐based bioreporter for the in vivo detection of novel biocatalysts
The use of bioreporters in high‐throughput screening for small molecules is generally laborious and/or expensive. The technology can be simplified by coupling the generation of a desired compound to cell survival, causing only positive cells to stay in the pool of generated variants. Here, a dual se...
Autores principales: | van Rossum, Teunke, Muras, Aleksandra, Baur, Marco J.J., Creutzburg, Sjoerd C.A., van der Oost, John, Kengen, Servé W.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404197/ https://www.ncbi.nlm.nih.gov/pubmed/28393499 http://dx.doi.org/10.1111/1751-7915.12612 |
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