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MR-guided parenchymal delivery of adeno-associated viral vector serotype 5 in non-human primate brain

The present study was designed to characterize transduction of non-human primate brain and spinal cord with AAV5 viral vector after parenchymal delivery. AAV5-CAG-GFP (1 × 10(13) vector genomes per milliliter (vg ml(−1))) was bilaterally infused either into putamen, thalamus or with the combination...

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Detalles Bibliográficos
Autores principales: Samaranch, L, Blits, B, San Sebastian, W, Hadaczek, P, Bringas, J, Sudhakar, V, Macayan, M, Pivirotto, P J, Petry, H, Bankiewicz, K S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404203/
https://www.ncbi.nlm.nih.gov/pubmed/28300083
http://dx.doi.org/10.1038/gt.2017.14