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MR-guided parenchymal delivery of adeno-associated viral vector serotype 5 in non-human primate brain
The present study was designed to characterize transduction of non-human primate brain and spinal cord with AAV5 viral vector after parenchymal delivery. AAV5-CAG-GFP (1 × 10(13) vector genomes per milliliter (vg ml(−1))) was bilaterally infused either into putamen, thalamus or with the combination...
Autores principales: | Samaranch, L, Blits, B, San Sebastian, W, Hadaczek, P, Bringas, J, Sudhakar, V, Macayan, M, Pivirotto, P J, Petry, H, Bankiewicz, K S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404203/ https://www.ncbi.nlm.nih.gov/pubmed/28300083 http://dx.doi.org/10.1038/gt.2017.14 |
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