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The Activity of JmjC Histone Lysine Demethylase KDM4A is Highly Sensitive to Oxygen Concentrations

[Image: see text] The JmjC histone lysine demethylases (KDMs) are epigenetic regulators involved in the removal of methyl groups from post-translationally modified lysyl residues within histone tails, modulating gene transcription. These enzymes require molecular oxygen for catalytic activity and, a...

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Detalles Bibliográficos
Autores principales:	Hancock, Rebecca L, Masson, Norma, Dunne, Kate, Flashman, Emily, Kawamura, Akane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2017
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404277/ https://www.ncbi.nlm.nih.gov/pubmed/28051298 http://dx.doi.org/10.1021/acschembio.6b00958

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