Cargando…

The malaria testing and treatment landscape in the southern Lao People’s Democratic Republic (PDR)

BACKGROUND: In the context of national and regional goals to eliminate malaria by 2030, the Center for Malaria Parasitology and Entomology in the Lao PDR is implementing strategies to ensure all malaria cases are detected and appropriately treated with first-line artemisinin combination therapy, art...

Descripción completa

Detalles Bibliográficos
Autor principal: Phanalasy, Saysana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404290/
https://www.ncbi.nlm.nih.gov/pubmed/28438155
http://dx.doi.org/10.1186/s12936-017-1769-0
_version_ 1783231569089003520
author Phanalasy, Saysana
author_facet Phanalasy, Saysana
collection PubMed
description BACKGROUND: In the context of national and regional goals to eliminate malaria by 2030, the Center for Malaria Parasitology and Entomology in the Lao PDR is implementing strategies to ensure all malaria cases are detected and appropriately treated with first-line artemisinin combination therapy, artemether–lumefantrine (AL). Timely and relevant evidence to inform policies and strategies is needed to ensure the most effective and efficient use of resources, and to accelerate progress towards elimination goals. A 2015 outlet survey conducted in five provinces of the southern Lao PDR was the first of its kind to study the total market for malaria treatments and diagnostics. The sub-national outlet survey was designed to describe the market and to assess public and private sector readiness and performance for malaria case management. Additionally, key indicators were estimated among private outlets within districts with and without a Public Private Mix (PPM) programme. RESULTS: Over half of anti-malarial stockists were public sector (65.1%). In the private sector, pharmacies most commonly stocked anti-malarials, although anti-malarials were also found in private health facilities, drug stores, general retailers, and itinerant drug vendors. Nearly all anti-malarial stocking public health facilities had AL (99.5%) and 90.8% had confirmatory testing. Fewer than half of anti-malarial stocking private outlets stocked AL (40.8%) and malaria testing (43.5%). Chloroquine has not been a first-line treatment for Plasmodium falciparum malaria since 2005 and Plasmodium vivax since 2011 yet private sector availability was 77.6% and chloroquine accounted for 62.2% of the total anti-malarial market share. AL and confirmatory testing availability were higher in private outlets in PPM (68.1, 72.6%) versus non-PPM districts (2.5, 12.1%). Chloroquine was available in 63.6% of PPM and 96.7% of non-PPM-district outlets, and was the most commonly distributed anti-malarial among private outlets in both PPM (61.7%) and non-PPM districts (99.1%). CONCLUSIONS: Public sector outlets in the southern Lao PDR are typically equipped to test and appropriately treat malaria. There is need to address widespread private sector availability and distribution of chloroquine. The PPM programme has improved private provider readiness to manage malaria according to national guidelines. However, supporting interventions to address provider and consumer behaviours are needed to further drive uptake. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12936-017-1769-0) contains supplementary material, which is available to authorized users.
format Online
Article
Text
id pubmed-5404290
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-54042902017-04-27 The malaria testing and treatment landscape in the southern Lao People’s Democratic Republic (PDR) Phanalasy, Saysana Malar J Research BACKGROUND: In the context of national and regional goals to eliminate malaria by 2030, the Center for Malaria Parasitology and Entomology in the Lao PDR is implementing strategies to ensure all malaria cases are detected and appropriately treated with first-line artemisinin combination therapy, artemether–lumefantrine (AL). Timely and relevant evidence to inform policies and strategies is needed to ensure the most effective and efficient use of resources, and to accelerate progress towards elimination goals. A 2015 outlet survey conducted in five provinces of the southern Lao PDR was the first of its kind to study the total market for malaria treatments and diagnostics. The sub-national outlet survey was designed to describe the market and to assess public and private sector readiness and performance for malaria case management. Additionally, key indicators were estimated among private outlets within districts with and without a Public Private Mix (PPM) programme. RESULTS: Over half of anti-malarial stockists were public sector (65.1%). In the private sector, pharmacies most commonly stocked anti-malarials, although anti-malarials were also found in private health facilities, drug stores, general retailers, and itinerant drug vendors. Nearly all anti-malarial stocking public health facilities had AL (99.5%) and 90.8% had confirmatory testing. Fewer than half of anti-malarial stocking private outlets stocked AL (40.8%) and malaria testing (43.5%). Chloroquine has not been a first-line treatment for Plasmodium falciparum malaria since 2005 and Plasmodium vivax since 2011 yet private sector availability was 77.6% and chloroquine accounted for 62.2% of the total anti-malarial market share. AL and confirmatory testing availability were higher in private outlets in PPM (68.1, 72.6%) versus non-PPM districts (2.5, 12.1%). Chloroquine was available in 63.6% of PPM and 96.7% of non-PPM-district outlets, and was the most commonly distributed anti-malarial among private outlets in both PPM (61.7%) and non-PPM districts (99.1%). CONCLUSIONS: Public sector outlets in the southern Lao PDR are typically equipped to test and appropriately treat malaria. There is need to address widespread private sector availability and distribution of chloroquine. The PPM programme has improved private provider readiness to manage malaria according to national guidelines. However, supporting interventions to address provider and consumer behaviours are needed to further drive uptake. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12936-017-1769-0) contains supplementary material, which is available to authorized users. BioMed Central 2017-04-25 /pmc/articles/PMC5404290/ /pubmed/28438155 http://dx.doi.org/10.1186/s12936-017-1769-0 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Phanalasy, Saysana
The malaria testing and treatment landscape in the southern Lao People’s Democratic Republic (PDR)
title The malaria testing and treatment landscape in the southern Lao People’s Democratic Republic (PDR)
title_full The malaria testing and treatment landscape in the southern Lao People’s Democratic Republic (PDR)
title_fullStr The malaria testing and treatment landscape in the southern Lao People’s Democratic Republic (PDR)
title_full_unstemmed The malaria testing and treatment landscape in the southern Lao People’s Democratic Republic (PDR)
title_short The malaria testing and treatment landscape in the southern Lao People’s Democratic Republic (PDR)
title_sort malaria testing and treatment landscape in the southern lao people’s democratic republic (pdr)
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404290/
https://www.ncbi.nlm.nih.gov/pubmed/28438155
http://dx.doi.org/10.1186/s12936-017-1769-0
work_keys_str_mv AT themalariatestingandtreatmentlandscapeinthesouthernlaopeoplesdemocraticrepublicpdr
AT phanalasysaysana themalariatestingandtreatmentlandscapeinthesouthernlaopeoplesdemocraticrepublicpdr
AT malariatestingandtreatmentlandscapeinthesouthernlaopeoplesdemocraticrepublicpdr
AT phanalasysaysana malariatestingandtreatmentlandscapeinthesouthernlaopeoplesdemocraticrepublicpdr