Cargando…
Estimating the annual burden of tick-borne encephalitis to inform vaccination policy, Slovenia, 2009 to 2013
With an annual incidence between 8 and 15 per 100,000 population in the period from 2009 to 2013, Slovenia has one of the highest notified incidences of tick-borne encephalitis (TBE) in Europe. TBE vaccination coverage remains at about 7.3%. To inform vaccination policy, we used surveillance data fr...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Centre for Disease Prevention and Control (ECDC)
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404479/ https://www.ncbi.nlm.nih.gov/pubmed/28449731 http://dx.doi.org/10.2807/1560-7917.ES.2017.22.16.30509 |
_version_ | 1783231606504292352 |
---|---|
author | Fafangel, Mario Cassini, Alessandro Colzani, Edoardo Klavs, Irena Grgič Vitek, Marta Učakar, Veronika Muehlen, Marion Vudrag, Marko Kraigher, Alenka |
author_facet | Fafangel, Mario Cassini, Alessandro Colzani, Edoardo Klavs, Irena Grgič Vitek, Marta Učakar, Veronika Muehlen, Marion Vudrag, Marko Kraigher, Alenka |
author_sort | Fafangel, Mario |
collection | PubMed |
description | With an annual incidence between 8 and 15 per 100,000 population in the period from 2009 to 2013, Slovenia has one of the highest notified incidences of tick-borne encephalitis (TBE) in Europe. TBE vaccination coverage remains at about 7.3%. To inform vaccination policy, we used surveillance data from 2009 to 2013 to calculate the overall and age- and sex-specific mean annual TBE incidence. We estimated disability-adjusted life years (DALYs) with 95% uncertainty intervals (UI), using the Burden of Communicable Diseases in Europe approach from the European Centre for Disease Prevention and Control. The mean annual incidence was 11.6 per 100,000 population, peaking in older age groups (50–74 years: 18.5/100,000) while relatively lower among children (5–14 years: 10.2/100,000). We estimated an overall 10.95 DALYs per 100,000 population per year (95% UI: 10.25-11.65). In contrast to the TBE incidence, the disease burden in children aged 5–14 years was higher than in adults aged 50–74 years: 17.31 (95% UI: 14.58–20.08) and 11.58 (95% UI: 10.25–12.91) DALYs per 100,000 stratum-specific population, respectively. In a limited resource setting where prioritisation of TBE vaccination strategies is required, vaccination programmes targeting children may have a higher impact on disease burden. |
format | Online Article Text |
id | pubmed-5404479 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | European Centre for Disease Prevention and Control (ECDC) |
record_format | MEDLINE/PubMed |
spelling | pubmed-54044792017-05-15 Estimating the annual burden of tick-borne encephalitis to inform vaccination policy, Slovenia, 2009 to 2013 Fafangel, Mario Cassini, Alessandro Colzani, Edoardo Klavs, Irena Grgič Vitek, Marta Učakar, Veronika Muehlen, Marion Vudrag, Marko Kraigher, Alenka Euro Surveill Research Article With an annual incidence between 8 and 15 per 100,000 population in the period from 2009 to 2013, Slovenia has one of the highest notified incidences of tick-borne encephalitis (TBE) in Europe. TBE vaccination coverage remains at about 7.3%. To inform vaccination policy, we used surveillance data from 2009 to 2013 to calculate the overall and age- and sex-specific mean annual TBE incidence. We estimated disability-adjusted life years (DALYs) with 95% uncertainty intervals (UI), using the Burden of Communicable Diseases in Europe approach from the European Centre for Disease Prevention and Control. The mean annual incidence was 11.6 per 100,000 population, peaking in older age groups (50–74 years: 18.5/100,000) while relatively lower among children (5–14 years: 10.2/100,000). We estimated an overall 10.95 DALYs per 100,000 population per year (95% UI: 10.25-11.65). In contrast to the TBE incidence, the disease burden in children aged 5–14 years was higher than in adults aged 50–74 years: 17.31 (95% UI: 14.58–20.08) and 11.58 (95% UI: 10.25–12.91) DALYs per 100,000 stratum-specific population, respectively. In a limited resource setting where prioritisation of TBE vaccination strategies is required, vaccination programmes targeting children may have a higher impact on disease burden. European Centre for Disease Prevention and Control (ECDC) 2017-04-20 /pmc/articles/PMC5404479/ /pubmed/28449731 http://dx.doi.org/10.2807/1560-7917.ES.2017.22.16.30509 Text en This article is copyright of The Authors, 2017. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made. |
spellingShingle | Research Article Fafangel, Mario Cassini, Alessandro Colzani, Edoardo Klavs, Irena Grgič Vitek, Marta Učakar, Veronika Muehlen, Marion Vudrag, Marko Kraigher, Alenka Estimating the annual burden of tick-borne encephalitis to inform vaccination policy, Slovenia, 2009 to 2013 |
title | Estimating the annual burden of tick-borne encephalitis to inform vaccination policy, Slovenia, 2009 to 2013 |
title_full | Estimating the annual burden of tick-borne encephalitis to inform vaccination policy, Slovenia, 2009 to 2013 |
title_fullStr | Estimating the annual burden of tick-borne encephalitis to inform vaccination policy, Slovenia, 2009 to 2013 |
title_full_unstemmed | Estimating the annual burden of tick-borne encephalitis to inform vaccination policy, Slovenia, 2009 to 2013 |
title_short | Estimating the annual burden of tick-borne encephalitis to inform vaccination policy, Slovenia, 2009 to 2013 |
title_sort | estimating the annual burden of tick-borne encephalitis to inform vaccination policy, slovenia, 2009 to 2013 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404479/ https://www.ncbi.nlm.nih.gov/pubmed/28449731 http://dx.doi.org/10.2807/1560-7917.ES.2017.22.16.30509 |
work_keys_str_mv | AT fafangelmario estimatingtheannualburdenoftickborneencephalitistoinformvaccinationpolicyslovenia2009to2013 AT cassinialessandro estimatingtheannualburdenoftickborneencephalitistoinformvaccinationpolicyslovenia2009to2013 AT colzaniedoardo estimatingtheannualburdenoftickborneencephalitistoinformvaccinationpolicyslovenia2009to2013 AT klavsirena estimatingtheannualburdenoftickborneencephalitistoinformvaccinationpolicyslovenia2009to2013 AT grgicvitekmarta estimatingtheannualburdenoftickborneencephalitistoinformvaccinationpolicyslovenia2009to2013 AT ucakarveronika estimatingtheannualburdenoftickborneencephalitistoinformvaccinationpolicyslovenia2009to2013 AT muehlenmarion estimatingtheannualburdenoftickborneencephalitistoinformvaccinationpolicyslovenia2009to2013 AT vudragmarko estimatingtheannualburdenoftickborneencephalitistoinformvaccinationpolicyslovenia2009to2013 AT kraigheralenka estimatingtheannualburdenoftickborneencephalitistoinformvaccinationpolicyslovenia2009to2013 |