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Simplified Reversed Chloroquines To Overcome Malaria Resistance to Quinoline-Based Drugs
Building on our earlier work of attaching a chemosensitizer (reversal agent) to a known drug pharmacophore, we have now expanded the structure-activity relationship study to include simplified versions of the chemosensitizer. The change from two aromatic rings in this head group to a single ring doe...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404532/ https://www.ncbi.nlm.nih.gov/pubmed/28193646 http://dx.doi.org/10.1128/AAC.01913-16 |