Microbiota-activated CD103(+) DCs stemming from microbiota adaptation specifically drive γδT17 proliferation and activation

BACKGROUND: IL-17-producing γδT cells (γδT17) promote autoinflammatory diseases and cancers. Yet, γδT17 peripheral regulation has not been thoroughly explored especially in the context of microbiota-host interaction. The potent antigen-presenting CD103(+) dendritic cell (DC) is a key immune player i...

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Detalles Bibliográficos
Autores principales: Fleming, Chris, Cai, Yihua, Sun, Xuan, Jala, Venkatakrishna R., Xue, Feng, Morrissey, Samantha, Wei, Yu-ling, Chien, Yueh-hsiu, Zhang, Huang-ge, Haribabu, Bodduluri, Huang, Jian, Yan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404689/
https://www.ncbi.nlm.nih.gov/pubmed/28438184
http://dx.doi.org/10.1186/s40168-017-0263-9

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