Cargando…

ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approaches

As a result of the association of a common polymorphism (rs2231142, Q141K) in the ATP-binding cassette G2 (ABCG2) transporter with serum urate concentration in a genome-wide association study, it was revealed that ABCG2 is an important uric acid transporter. This review discusses the relevance of AB...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cleophas, MC, Joosten, LA, Stamp, LK, Dalbeth, N, Woodward, OM, Merriman, Tony R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404803/ https://www.ncbi.nlm.nih.gov/pubmed/28461764 http://dx.doi.org/10.2147/PGPM.S105854

Ejemplares similares

Population-specific association between ABCG2 variants and tophaceous disease in people with gout
por: He, Wendy, et al.
Publicado: (2017)

Pleiotropic effect of the ABCG2 gene in gout: involvement in serum urate levels and progression from hyperuricemia to gout
por: Wrigley, Rebekah, et al.
Publicado: (2020)

The genetics of gout: towards personalised medicine?
por: Dalbeth, Nicola, et al.
Publicado: (2017)

The ABCG2 Q141K hyperuricemia and gout associated variant illuminates the physiology of human urate excretion
por: Hoque, Kazi Mirajul, et al.
Publicado: (2020)

Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout
por: Rasheed, Humaira, et al.
Publicado: (2017)

Influence of the ABCG2 gout risk 141 K allele on urate metabolism during a fructose challenge
por: Dalbeth, Nicola, et al.
Publicado: (2014)

The relationship of apolipoprotein B and very low density lipoprotein triglyceride with hyperuricemia and gout
por: Rasheed, Humaira, et al.
Publicado: (2014)

Sugar Sweetened Beverage Consumption among Adults with Gout or Type 2 Diabetes
por: Murphy, Rinki, et al.
Publicado: (2015)

The relationship between ferritin and urate levels and risk of gout
por: Fatima, Tahzeeb, et al.
Publicado: (2018)

Mediation analysis to understand genetic relationships between habitual coffee intake and gout
por: Hutton, Joseph, et al.
Publicado: (2018)

Gout and the risk of COVID-19 diagnosis and death in the UK Biobank: a population-based study
por: Topless, Ruth K, et al.
Publicado: (2022)

Performance of gout definitions for genetic epidemiological studies: analysis of UK Biobank
por: Cadzow, Murray, et al.
Publicado: (2017)

Interactions between serum urate-associated genetic variants and sex on gout risk: analysis of the UK Biobank
por: Narang, Ravi K., et al.
Publicado: (2019)

Gout, Rheumatoid Arthritis, and the Risk of Death Related to Coronavirus Disease 2019: An Analysis of the UK Biobank
por: Topless, Ruth K., et al.
Publicado: (2021)

Body mass index modulates the relationship of sugar-sweetened beverage intake with serum urate concentrations and gout
por: Dalbeth, Nicola, et al.
Publicado: (2015)

Multiple common and rare variants of ABCG2 cause gout
por: Higashino, Toshihide, et al.
Publicado: (2017)

Sugar-sweetened beverage consumption: a risk factor for prevalent gout with SLC2A9 genotype-specific effects on serum urate and risk of gout
por: Batt, Caitlin, et al.
Publicado: (2014)

Longitudinal development of incident gout from low-normal baseline serum urate concentrations: individual participant data analysis
por: Robinson, Philip C., et al.
Publicado: (2021)

Is repeat serum urate testing superior to a single test to predict incident gout over time?
por: Stewart, Sarah, et al.
Publicado: (2022)

Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout
por: McKinney, Cushla, et al.
Publicado: (2015)

The SLC2A9 nonsynonymous Arg265His variant and gout: evidence for a population-specific effect on severity
por: Hollis-Moffatt, Jade E, et al.
Publicado: (2011)

Positive association of tomato consumption with serum urate: support for tomato consumption as an anecdotal trigger of gout flares
por: Flynn, Tanya J, et al.
Publicado: (2015)

Inequities in people with gout: a focus on Māori (Indigenous People) of Aotearoa New Zealand
por: Te Karu, Leanne, et al.
Publicado: (2021)

Genetic polymorphisms and decreased protein expression of ABCG2 urate transporters are associated with susceptibility to gout, disease severity and renal-overload hyperuricemia
por: Pálinkás, Márton, et al.
Publicado: (2022)

Functional Polymorphisms of the ABCG2 Gene Are Associated with Gout Disease in the Chinese Han Male Population
por: Zhou, Danqiu, et al.
Publicado: (2014)

Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients
por: Nakayama, Akiyoshi, et al.
Publicado: (2020)

An update on the genetic architecture of hyperuricemia and gout
por: Merriman, Tony R
Publicado: (2015)

Association of the lipoprotein receptor-related protein 2 gene with gout and non-additive interaction with alcohol consumption
por: Rasheed, Humaira, et al.
Publicado: (2013)

Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case-control sample sets reveals multiple ancestral-specific effects
por: Flynn, Tanya J, et al.
Publicado: (2013)

Effect of body mass index on serum urate and renal uric acid handling responses to an oral inosine load: experimental intervention study in healthy volunteers
por: Dalbeth, Nicola, et al.
Publicado: (2020)

A Polynesian-specific copy number variant encompassing the MICA gene associates with gout
por: Wang, Ke, et al.
Publicado: (2022)

Polymorphisms of ABCG2 and SLC22A12 Genes Associated with Gout Risk in Vietnamese Population
por: Thuy Duong, Nguyen, et al.
Publicado: (2019)

The Role of ABCG2 in the Pathogenesis of Primary Hyperuricemia and Gout—An Update
por: Eckenstaler, Robert, et al.
Publicado: (2021)

The renal urate transporter SLC17A1 locus: confirmation of association with gout
por: Hollis-Moffatt, Jade E, et al.
Publicado: (2012)

ABCG2 gene polymorphism rs2231142 is associated with gout comorbidities but not allopurinol response in primary gout patients of a Chinese Han male population
por: Zhang, Keke, et al.
Publicado: (2019)

A comprehensive analysis of the association of common variants of ABCG2 with gout
por: Yu, Kuang-Hui, et al.
Publicado: (2017)

Racial and Sex Disparities in Gout Prevalence Among US Adults
por: McCormick, Natalie, et al.
Publicado: (2022)

Gout. Imaging of gout: findings and utility
por: Perez-Ruiz, Fernando, et al.
Publicado: (2009)

The Toll-Like Receptor 4 (TLR4) Variant rs2149356 and Risk of Gout in European and Polynesian Sample Sets
por: Rasheed, Humaira, et al.
Publicado: (2016)

Gout Remission as a Goal of Urate-Lowering Therapy: A Critical Review
por: Tabi-Amponsah, Adwoa Dansoa, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6gboc28kc8vfa33iknch7rbto0