A Ratiometric Sensor for Imaging Insulin Secretion in Single β Cells

Despite the urgent need for assays to visualize insulin secretion there is to date no reliable method available for measuring insulin release from single cells. To address this need, we developed a genetically encoded reporter termed RINS1 based on proinsulin superfolder GFP (sfGFP) and mCherry fusi...

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Detalles Bibliográficos
Autores principales: Schifferer, Martina, Yushchenko, Dmytro A., Stein, Frank, Bolbat, Andrey, Schultz, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404835/
https://www.ncbi.nlm.nih.gov/pubmed/28366620
http://dx.doi.org/10.1016/j.chembiol.2017.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404835/
https://www.ncbi.nlm.nih.gov/pubmed/28366620
http://dx.doi.org/10.1016/j.chembiol.2017.03.001

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