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A Ratiometric Sensor for Imaging Insulin Secretion in Single β Cells
Despite the urgent need for assays to visualize insulin secretion there is to date no reliable method available for measuring insulin release from single cells. To address this need, we developed a genetically encoded reporter termed RINS1 based on proinsulin superfolder GFP (sfGFP) and mCherry fusi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404835/ https://www.ncbi.nlm.nih.gov/pubmed/28366620 http://dx.doi.org/10.1016/j.chembiol.2017.03.001 |