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Regional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor-β signaling

Pericytes regulate key neurovascular functions of the brain. Studies in pericyte-deficient transgenic mice with aberrant signaling between endothelial-derived platelet-derived growth factor BB (PDGF-BB) and platelet-derived growth factor receptor β (PDGFRβ) in pericytes have contributed to better un...

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Detalles Bibliográficos
Autores principales:	Nikolakopoulou, Angeliki Maria, Zhao, Zhen, Montagne, Axel, Zlokovic, Berislav V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404855/ https://www.ncbi.nlm.nih.gov/pubmed/28441414 http://dx.doi.org/10.1371/journal.pone.0176225

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