Parathyroid hormone's enhancement of bones' osteogenic response to loading is affected by ageing in a dose- and time-dependent manner

Decreased effectiveness of bones' adaptive response to mechanical loading contributes to age-related bone loss. In young mice, intermittent administration of parathyroid hormone (iPTH) at 20–80 μg/kg/day interacts synergistically with artificially applied loading to increase bone mass. Here we...

Descripción completa

Detalles Bibliográficos
Autores principales: Meakin, Lee B, Todd, Henry, Delisser, Peter J, Galea, Gabriel L, Moustafa, Alaa, Lanyon, Lance E, Windahl, Sara H, Price, Joanna S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2017
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404907/
https://www.ncbi.nlm.nih.gov/pubmed/28249797
http://dx.doi.org/10.1016/j.bone.2017.02.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404907/
https://www.ncbi.nlm.nih.gov/pubmed/28249797
http://dx.doi.org/10.1016/j.bone.2017.02.009

Ejemplares similares