Capillary K(+)-sensing initiates retrograde hyperpolarization to locally increase cerebral blood flow

Blood flow into the brain is dynamically regulated to satisfy the changing metabolic requirements of neurons, but how this is accomplished has remained unclear. Here, we demonstrate a central role for capillary endothelial cells in sensing neural activity and communicating it to upstream arterioles...

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Detalles Bibliográficos
Autores principales: Longden, Thomas A., Dabertrand, Fabrice, Koide, Masayo, Gonzales, Albert L., Tykocki, Nathan R., Brayden, Joseph E., Hill-Eubanks, David, Nelson, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404963/
https://www.ncbi.nlm.nih.gov/pubmed/28319610
http://dx.doi.org/10.1038/nn.4533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404963/
https://www.ncbi.nlm.nih.gov/pubmed/28319610
http://dx.doi.org/10.1038/nn.4533

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