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Capillary K(+)-sensing initiates retrograde hyperpolarization to locally increase cerebral blood flow
Blood flow into the brain is dynamically regulated to satisfy the changing metabolic requirements of neurons, but how this is accomplished has remained unclear. Here, we demonstrate a central role for capillary endothelial cells in sensing neural activity and communicating it to upstream arterioles...
Autores principales: | Longden, Thomas A., Dabertrand, Fabrice, Koide, Masayo, Gonzales, Albert L., Tykocki, Nathan R., Brayden, Joseph E., Hill-Eubanks, David, Nelson, Mark T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404963/ https://www.ncbi.nlm.nih.gov/pubmed/28319610 http://dx.doi.org/10.1038/nn.4533 |
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