Cargando…

Genetic Determinants of Adiponectin Regulation Revealed by Pregnancy

OBJECTIVE: We investigated genetic determinants of adiponectin during pregnancy to reveal novel biology of adipocyte regulation. METHODS: We conducted a genome-wide association study in 1,322 pregnant women from the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study with adiponectin measured a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hivert, Marie-France, Scholtens, Denise M., Allard, Catherine, Nodzenski, Michael, Bouchard, Luigi, Brisson, Diane, Lowe, Lynn P., McDowell, Ian, Reddy, Tim, Dastani, Zari, Richards, J. Brent, Hayes, M. Geoffrey, Lowe, William L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404994/ https://www.ncbi.nlm.nih.gov/pubmed/28317342 http://dx.doi.org/10.1002/oby.21805

Ejemplares similares

Genetic Determinants of Glycemic Traits and the Risk of Gestational Diabetes Mellitus
por: Powe, Camille E., et al.
Publicado: (2018)

Transversions have larger regulatory effects than transitions
por: Guo, Cong, et al.
Publicado: (2017)

Placental Adiponectin Gene DNA Methylation Levels Are Associated With Mothers’ Blood Glucose Concentration
por: Bouchard, Luigi, et al.
Publicado: (2012)

Network Approaches to Integrate Analyses of Genetics and Metabolomics Data with Applications to Fetal Programming Studies
por: Kuang, Alan, et al.
Publicado: (2022)

Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort
por: Vockley, Christopher M., et al.
Publicado: (2015)

Genetic Loci and Physiologic Pathways Involved in Gestational Diabetes Mellitus Implicated Through Clustering
por: Powe, Camille E., et al.
Publicado: (2021)

Metabolic Networks and Metabolites Underlie Associations Between Maternal Glucose During Pregnancy and Newborn Size at Birth
por: Scholtens, Denise M., et al.
Publicado: (2016)

Metabomxtr: an R package for mixture-model analysis of non-targeted metabolomics data
por: Nodzenski, Michael, et al.
Publicado: (2014)

OR18-06 Metabolomic And Genetic Architecture Of Gestational Diabetes Subtypes
por: Lee, Kristen, et al.
Publicado: (2023)

Targeted Metabolomics Demonstrates Distinct and Overlapping Maternal Metabolites Associated With BMI, Glucose, and Insulin Sensitivity During Pregnancy Across Four Ancestry Groups
por: Jacob, Saya, et al.
Publicado: (2017)

SAT-124 Hyperglycemia and Adverse Pregnancy Outcome Follow-Up Study (HAPO FUS): Newborn Anthropometrics and Childhood Glucose Metabolism
por: Bianco, Monica, et al.
Publicado: (2019)

Identification of HKDC1 and BACE2 as Genes Influencing Glycemic Traits During Pregnancy Through Genome-Wide Association Studies
por: Hayes, M. Geoffrey, et al.
Publicado: (2013)

RF12 | PSUN105 Cord Blood Leptin and Childhood Adiposity Outcomes in the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study
por: DeLacey, Sean, et al.
Publicado: (2022)

SAT-123 Burden of Type 2 Diabetes Genetic Risk Alleles Differs Among Physiologic Subtypes of Gestational Diabetes Mellitus
por: Powe, Camille, et al.
Publicado: (2019)

The Empirical Power of Rare Variant Association Methods: Results from Sanger Sequencing in 1,998 Individuals
por: Ladouceur, Martin, et al.
Publicado: (2012)

An Efficient Paradigm for Genetic Epidemiology Cohort Creation
por: Ladouceur, Martin, et al.
Publicado: (2010)

Erratum. Maternal BMI and Glycemia Impact the Fetal Metabolome. Diabetes Care 2017;40:902–910
por: Lowe, William L., et al.
Publicado: (2018)

Maternal BMI and Glycemia Impact the Fetal Metabolome
por: Lowe, William L., et al.
Publicado: (2017)

Interplay of Placental DNA Methylation and Maternal Insulin Sensitivity in Pregnancy
por: Hivert, Marie-France, et al.
Publicado: (2020)

Metabolomic and genetic associations with insulin resistance in pregnancy
por: Liu, Yu, et al.
Publicado: (2020)

PPARGC1α gene DNA methylation variations in human placenta mediate the link between maternal hyperglycemia and leptin levels in newborns
por: Côté, Sandra, et al.
Publicado: (2016)

Associations between a fetal imprinted gene allele score and late pregnancy maternal glucose concentrations
por: Petry, C.J., et al.
Publicado: (2017)

Maternal glycemia in pregnancy is longitudinally associated with blood DNAm variation at the FSD1L gene from birth to 5 years of age
por: Taschereau, Amélie, et al.
Publicado: (2023)

Multiple Regression Methods Show Great Potential for Rare Variant Association Tests
por: Xu, ChangJiang, et al.
Publicado: (2012)

Leptin and adiponectin DNA methylation levels in adipose tissues and blood cells are associated with BMI, waist girth and LDL-cholesterol levels in severely obese men and women
por: Houde, Andrée-Anne, et al.
Publicado: (2015)

Fetal epigenetic programming of adipokines
por: Houde, Andrée-Anne, et al.
Publicado: (2013)

SERPINE1 DNA Methylation Levels Quantified in Blood Cells at Five Years of Age Are Associated with Adiposity and Plasma PAI-1 Levels at Five Years of Age
por: Taschereau, Amelie, et al.
Publicado: (2022)

Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): Maternal Gestational Diabetes Mellitus and Childhood Glucose Metabolism
por: Lowe, William L., et al.
Publicado: (2019)

All thresholds of maternal hyperglycaemia from the WHO 2013 criteria for gestational diabetes identify women with a higher genetic risk for type 2 diabetes
por: Hughes, Alice E., et al.
Publicado: (2021)

Mixture model normalization for non-targeted gas chromatography/mass spectrometry metabolomics data
por: Reisetter, Anna C., et al.
Publicado: (2017)

Validation of a DNA methylation reference panel for the estimation of nucleated cells types in cord blood
por: Cardenas, Andres, et al.
Publicado: (2016)

Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies. Diabetes 2013;62:3282–3291
por: Hayes, MG, et al.
Publicado: (2013)

Lower Adiponectin Levels at First Trimester of Pregnancy Are Associated With Increased Insulin Resistance and Higher Risk of Developing Gestational Diabetes Mellitus
por: Lacroix, Marilyn, et al.
Publicado: (2013)

Placental RNA sequencing implicates IGFBP1 in insulin sensitivity during pregnancy and in gestational diabetes
por: Hivert, Marie-France, et al.
Publicado: (2023)

Salivary pH as a marker of plasma adiponectin concentrations in Women
por: Tremblay, Monique, et al.
Publicado: (2012)

Metabolomics Reveals Broad-Scale Metabolic Perturbations in Hyperglycemic Mothers During Pregnancy
por: Scholtens, Denise M., et al.
Publicado: (2014)

Epithelial-Myoepithelial Carcinoma of the Breast with Rhabdoid Features
por: Grenier, Karl, et al.
Publicado: (2020)

Common Variants in the Adiponectin Gene (ADIPOQ) Associated With Plasma Adiponectin Levels, Type 2 Diabetes, and Diabetes-Related Quantitative Traits: The Framingham Offspring Study
por: Hivert, Marie-France, et al.
Publicado: (2008)

Copy number variation of the APC gene is associated with regulation of bone mineral density()
por: Chew, Shelby, et al.
Publicado: (2012)

Associations between Cord Blood Leptin Levels and Childhood Adiposity Differ by Sex and Age at Adiposity Assessment
por: Blais, Kasandra, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_c48r6m0kk0gf925mci3j823dn0