Proteomic Analysis Reveals Autophagy as Pro-Survival Pathway Elicited by Long-Term Exposure with 5-Azacitidine in High-Risk Myelodysplasia

Azacytidine (5-AZA) is the standard first-choice treatment for high-risk myelodysplasia (MDS) patients. However, the clinical outcome for those patients who interrupt treatment or whose disease failed to respond is very poor. In order to identify the cellular pathways that are modified by long-term...

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Detalles Bibliográficos
Autores principales: Romano, Alessandra, Giallongo, Cesarina, La Cava, Piera, Parrinello, Nunziatina L., Chiechi, Antonella, Vetro, Calogero, Tibullo, Daniele, Di Raimondo, Francesco, Liotta, Lance A., Espina, Virginia, Palumbo, Giuseppe A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405131/
https://www.ncbi.nlm.nih.gov/pubmed/28491035
http://dx.doi.org/10.3389/fphar.2017.00204

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