Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration

Tenofovir disoproxil fumarate (TDF) genotypic resistance defined by K65R/N and/or K70E/Q/G occurs in 20% to 60% of individuals with virological failure (VF) on a WHO-recommended TDF-containing first-line regimen. However, the full spectrum of reverse transcriptase (RT) mutations selected in individu...

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Detalles Bibliográficos
Autores principales: Rhee, Soo-Yon, Varghese, Vici, Holmes, Susan P., Van Zyl, Gert U., Steegen, Kim, Boyd, Mark A., Cooper, David A., Nsanzimana, Sabin, Saravanan, Shanmugam, Charpentier, Charlotte, de Oliveira, Tulio, Etiebet, Mary-Ann A., Garcia, Federico, Goedhals, Dominique, Gomes, Perpetua, Günthard, Huldrych F., Hamers, Raph L., Hoffmann, Christopher J, Hunt, Gillian, Jiamsakul, Awachana, Kaleebu, Pontiano, Kanki, Phyllis, Kantor, Rami, Kerschberger, Bernhard, Marconi, Vincent C., D'amour Ndahimana, Jean, Ndembi, Nicaise, Ngo-Giang-Huong, Nicole, Rokx, Casper, Santoro, Maria M., Schapiro, Jonathan M., Schmidt, Daniel, Seu, Lillian, Sigaloff, Kim C.E., Sirivichayakul, Sunee, Skhosana, Lindiwe, Sunpath, Henry, Tang, Michele, Yang, Chunfu, Carmona, Sergio, Gupta, Ravindra K., Shafer, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405160/
https://www.ncbi.nlm.nih.gov/pubmed/28365230
http://dx.doi.org/10.1016/j.ebiom.2017.03.024

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