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Hepatitis C Virus Indirectly Disrupts DNA Damage-Induced p53 Responses by Activating Protein Kinase R

Many DNA tumor viruses promote cellular transformation by inactivating the critically important tumor suppressor protein p53. In contrast, it is not known whether p53 function is disrupted by hepatitis C virus (HCV), a unique, oncogenic RNA virus that is the leading infectious cause of liver cancer...

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Detalles Bibliográficos
Autores principales:	Mitchell, Jonathan K., Midkiff, Bentley R., Israelow, Benjamin, Evans, Matthew J., Lanford, Robert E., Walker, Christopher M., Lemon, Stanley M., McGivern, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405228/ https://www.ncbi.nlm.nih.gov/pubmed/28442604 http://dx.doi.org/10.1128/mBio.00121-17

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