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Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model

Alzheimer’s disease is characterized by the deposition of amyloid-β as extracellular plaques and hyperphosphorylated tau as intracellular neurofibrillary tangles. Tau pathology characterizes not only Alzheimer’s disease, but also many other tauopathies, presenting tau as an attractive therapeutic ta...

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Detalles Bibliográficos
Autores principales: Nisbet, Rebecca M., Van der Jeugd, Ann, Leinenga, Gerhard, Evans, Harrison T., Janowicz, Phillip W., Götz, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405237/
https://www.ncbi.nlm.nih.gov/pubmed/28379300
http://dx.doi.org/10.1093/brain/awx052