Cargando…
Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model
Alzheimer’s disease is characterized by the deposition of amyloid-β as extracellular plaques and hyperphosphorylated tau as intracellular neurofibrillary tangles. Tau pathology characterizes not only Alzheimer’s disease, but also many other tauopathies, presenting tau as an attractive therapeutic ta...
Autores principales: | Nisbet, Rebecca M., Van der Jeugd, Ann, Leinenga, Gerhard, Evans, Harrison T., Janowicz, Phillip W., Götz, Jürgen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405237/ https://www.ncbi.nlm.nih.gov/pubmed/28379300 http://dx.doi.org/10.1093/brain/awx052 |
Ejemplares similares
-
Ultrasound-mediated blood-brain barrier opening enhances delivery of therapeutically relevant formats of a tau-specific antibody
por: Janowicz, Phillip W., et al.
Publicado: (2019) -
Repeated ultrasound treatment of tau transgenic mice clears neuronal tau by autophagy and improves behavioral functions
por: Pandit, Rucha, et al.
Publicado: (2019) -
Tau antibody isotype induces differential effects following passive immunisation of tau transgenic mice
por: Bajracharya, Rinie, et al.
Publicado: (2021) -
What Renders TAU Toxic
por: Götz, Jürgen, et al.
Publicado: (2013) -
Accelerated aging exacerbates a pre‐existing pathology in a tau transgenic mouse model
por: Bodea, Liviu‐Gabriel, et al.
Publicado: (2017)