Whole-Genome Comparative Analysis of Salmonella enterica Serovar Newport Strains Reveals Lineage-Specific Divergence

Salmonella enterica subsp. enterica serovar Newport has been associated with various foodborne outbreaks in humans and animals. Phylogenetically, serovar Newport is one of several Salmonella serovars that are polyphyletic. To understand more about the polyphyletic nature of this serovar, six food, e...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Jie, Luo, Yan, Reed, Elizabeth, Bell, Rebecca, Brown, Eric W., Hoffmann, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405337/
https://www.ncbi.nlm.nih.gov/pubmed/28379364
http://dx.doi.org/10.1093/gbe/evx065
_version_ 1783231744901644288
author Zheng, Jie
Luo, Yan
Reed, Elizabeth
Bell, Rebecca
Brown, Eric W.
Hoffmann, Maria
author_facet Zheng, Jie
Luo, Yan
Reed, Elizabeth
Bell, Rebecca
Brown, Eric W.
Hoffmann, Maria
author_sort Zheng, Jie
collection PubMed
description Salmonella enterica subsp. enterica serovar Newport has been associated with various foodborne outbreaks in humans and animals. Phylogenetically, serovar Newport is one of several Salmonella serovars that are polyphyletic. To understand more about the polyphyletic nature of this serovar, six food, environment, and human isolates from different Newport lineages were selected for genome comparison analyses. Whole genome comparisons demonstrated that heterogeneity mostly occurred in the prophage regions. Lineage-specific characteristics were also present in the Salmonella pathogenicity islands and fimbrial operons.
format Online
Article
Text
id pubmed-5405337
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-54053372017-05-01 Whole-Genome Comparative Analysis of Salmonella enterica Serovar Newport Strains Reveals Lineage-Specific Divergence Zheng, Jie Luo, Yan Reed, Elizabeth Bell, Rebecca Brown, Eric W. Hoffmann, Maria Genome Biol Evol Genome Report Salmonella enterica subsp. enterica serovar Newport has been associated with various foodborne outbreaks in humans and animals. Phylogenetically, serovar Newport is one of several Salmonella serovars that are polyphyletic. To understand more about the polyphyletic nature of this serovar, six food, environment, and human isolates from different Newport lineages were selected for genome comparison analyses. Whole genome comparisons demonstrated that heterogeneity mostly occurred in the prophage regions. Lineage-specific characteristics were also present in the Salmonella pathogenicity islands and fimbrial operons. Oxford University Press 2017-04-01 /pmc/articles/PMC5405337/ /pubmed/28379364 http://dx.doi.org/10.1093/gbe/evx065 Text en Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution 2017. This work is written by US Government employees and is in the public domain in the US.
spellingShingle Genome Report
Zheng, Jie
Luo, Yan
Reed, Elizabeth
Bell, Rebecca
Brown, Eric W.
Hoffmann, Maria
Whole-Genome Comparative Analysis of Salmonella enterica Serovar Newport Strains Reveals Lineage-Specific Divergence
title Whole-Genome Comparative Analysis of Salmonella enterica Serovar Newport Strains Reveals Lineage-Specific Divergence
title_full Whole-Genome Comparative Analysis of Salmonella enterica Serovar Newport Strains Reveals Lineage-Specific Divergence
title_fullStr Whole-Genome Comparative Analysis of Salmonella enterica Serovar Newport Strains Reveals Lineage-Specific Divergence
title_full_unstemmed Whole-Genome Comparative Analysis of Salmonella enterica Serovar Newport Strains Reveals Lineage-Specific Divergence
title_short Whole-Genome Comparative Analysis of Salmonella enterica Serovar Newport Strains Reveals Lineage-Specific Divergence
title_sort whole-genome comparative analysis of salmonella enterica serovar newport strains reveals lineage-specific divergence
topic Genome Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405337/
https://www.ncbi.nlm.nih.gov/pubmed/28379364
http://dx.doi.org/10.1093/gbe/evx065
work_keys_str_mv AT zhengjie wholegenomecomparativeanalysisofsalmonellaentericaserovarnewportstrainsrevealslineagespecificdivergence
AT luoyan wholegenomecomparativeanalysisofsalmonellaentericaserovarnewportstrainsrevealslineagespecificdivergence
AT reedelizabeth wholegenomecomparativeanalysisofsalmonellaentericaserovarnewportstrainsrevealslineagespecificdivergence
AT bellrebecca wholegenomecomparativeanalysisofsalmonellaentericaserovarnewportstrainsrevealslineagespecificdivergence
AT brownericw wholegenomecomparativeanalysisofsalmonellaentericaserovarnewportstrainsrevealslineagespecificdivergence
AT hoffmannmaria wholegenomecomparativeanalysisofsalmonellaentericaserovarnewportstrainsrevealslineagespecificdivergence

Ejemplares similares