Cargando…
High Glucose Promotes CD36 Expression by Upregulating Peroxisome Proliferator-Activated Receptor γ Levels to Exacerbate Lipid Deposition in Renal Tubular Cells
Diabetic kidney disease (DKD) appears to be closely related to lipid deposition in kidney. The aim of this study was to determine whether high glucose (HG) exacerbated lipid deposition by increasing CD36 expression via AKT-PPARγ signaling pathway. Our results showed that HG activated AKT signaling p...
Autores principales: | Feng, Lei, Gu, Chengwu, Li, Yanxia, Huang, Jiasui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405368/ https://www.ncbi.nlm.nih.gov/pubmed/28497039 http://dx.doi.org/10.1155/2017/1414070 |
Ejemplares similares
-
Peroxisome Proliferator-Activator Receptor γ: A Link between Macrophage CD36 and Inflammation in Malaria Infection
por: Ren, Yi
Publicado: (2012) -
Activation of peroxisome proliferator-activated receptor γ inhibits vascular calcification by upregulating Klotho
por: Cheng, Lijuan, et al.
Publicado: (2017) -
MD001, a Novel Peroxisome Proliferator-activated Receptor α/γ Agonist, Improves Glucose and Lipid Metabolism
por: Kim, Seok-Ho, et al.
Publicado: (2019) -
WISP1 alleviates lipid deposition in macrophages via the PPARγ/CD36 pathway in the plaque formation of atherosclerosis
por: Liu, Dian, et al.
Publicado: (2020) -
Renal tubular epithelium-targeted peroxisome proliferator-activated receptor-γ maintains the epithelial phenotype and antagonizes renal fibrogenesis
por: Zhao, Min, et al.
Publicado: (2016)