Cargando…

Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features

Background. Hyperparathyroidism is underdiagnosed in pregnancy, yet early diagnosis is necessary for the potentially severe sequelae of hypercalcemia for both the woman and fetus. Case. A 31-year-old, gravida 3, para 0-0-2-0 at 32 weeks and 3 days of gestation, presented with preeclampsia with sever...

Descripción completa

Detalles Bibliográficos
Autores principales: Dale, Andrew G., Holbrook, Bradley D., Sobel, Lauren, Rappaport, Valerie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405398/
https://www.ncbi.nlm.nih.gov/pubmed/28487796
http://dx.doi.org/10.1155/2017/6061313
_version_ 1783231758807859200
author Dale, Andrew G.
Holbrook, Bradley D.
Sobel, Lauren
Rappaport, Valerie J.
author_facet Dale, Andrew G.
Holbrook, Bradley D.
Sobel, Lauren
Rappaport, Valerie J.
author_sort Dale, Andrew G.
collection PubMed
description Background. Hyperparathyroidism is underdiagnosed in pregnancy, yet early diagnosis is necessary for the potentially severe sequelae of hypercalcemia for both the woman and fetus. Case. A 31-year-old, gravida 3, para 0-0-2-0 at 32 weeks and 3 days of gestation, presented with preeclampsia with severe features concomitant with acute pancreatitis and known diabetes mellitus type 2. She was stabilized and delivered. In the postpartum period, her total calcium level remained elevated. Ionized calcium levels and parathyroid hormone levels were also elevated, and she was diagnosed with hyperparathyroidism. Conclusion. Hyperparathyroidism and hypercalcemia are risk factors for pancreatitis. Women who develop pancreatitis during pregnancy are at increased risk of developing preeclampsia. If elevated serum calcium is noted, it should be confirmed with ionized calcium level and parathyroid hormones as ionized calcium levels are unaffected by pregnancy.
format Online
Article
Text
id pubmed-5405398
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-54053982017-05-09 Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features Dale, Andrew G. Holbrook, Bradley D. Sobel, Lauren Rappaport, Valerie J. Case Rep Obstet Gynecol Case Report Background. Hyperparathyroidism is underdiagnosed in pregnancy, yet early diagnosis is necessary for the potentially severe sequelae of hypercalcemia for both the woman and fetus. Case. A 31-year-old, gravida 3, para 0-0-2-0 at 32 weeks and 3 days of gestation, presented with preeclampsia with severe features concomitant with acute pancreatitis and known diabetes mellitus type 2. She was stabilized and delivered. In the postpartum period, her total calcium level remained elevated. Ionized calcium levels and parathyroid hormone levels were also elevated, and she was diagnosed with hyperparathyroidism. Conclusion. Hyperparathyroidism and hypercalcemia are risk factors for pancreatitis. Women who develop pancreatitis during pregnancy are at increased risk of developing preeclampsia. If elevated serum calcium is noted, it should be confirmed with ionized calcium level and parathyroid hormones as ionized calcium levels are unaffected by pregnancy. Hindawi 2017 2017-04-11 /pmc/articles/PMC5405398/ /pubmed/28487796 http://dx.doi.org/10.1155/2017/6061313 Text en Copyright © 2017 Andrew G. Dale et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dale, Andrew G.
Holbrook, Bradley D.
Sobel, Lauren
Rappaport, Valerie J.
Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features
title Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features
title_full Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features
title_fullStr Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features
title_full_unstemmed Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features
title_short Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features
title_sort hyperparathyroidism in pregnancy leading to pancreatitis and preeclampsia with severe features
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405398/
https://www.ncbi.nlm.nih.gov/pubmed/28487796
http://dx.doi.org/10.1155/2017/6061313
work_keys_str_mv AT daleandrewg hyperparathyroidisminpregnancyleadingtopancreatitisandpreeclampsiawithseverefeatures
AT holbrookbradleyd hyperparathyroidisminpregnancyleadingtopancreatitisandpreeclampsiawithseverefeatures
AT sobellauren hyperparathyroidisminpregnancyleadingtopancreatitisandpreeclampsiawithseverefeatures
AT rappaportvaleriej hyperparathyroidisminpregnancyleadingtopancreatitisandpreeclampsiawithseverefeatures