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Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features
Background. Hyperparathyroidism is underdiagnosed in pregnancy, yet early diagnosis is necessary for the potentially severe sequelae of hypercalcemia for both the woman and fetus. Case. A 31-year-old, gravida 3, para 0-0-2-0 at 32 weeks and 3 days of gestation, presented with preeclampsia with sever...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405398/ https://www.ncbi.nlm.nih.gov/pubmed/28487796 http://dx.doi.org/10.1155/2017/6061313 |
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author | Dale, Andrew G. Holbrook, Bradley D. Sobel, Lauren Rappaport, Valerie J. |
author_facet | Dale, Andrew G. Holbrook, Bradley D. Sobel, Lauren Rappaport, Valerie J. |
author_sort | Dale, Andrew G. |
collection | PubMed |
description | Background. Hyperparathyroidism is underdiagnosed in pregnancy, yet early diagnosis is necessary for the potentially severe sequelae of hypercalcemia for both the woman and fetus. Case. A 31-year-old, gravida 3, para 0-0-2-0 at 32 weeks and 3 days of gestation, presented with preeclampsia with severe features concomitant with acute pancreatitis and known diabetes mellitus type 2. She was stabilized and delivered. In the postpartum period, her total calcium level remained elevated. Ionized calcium levels and parathyroid hormone levels were also elevated, and she was diagnosed with hyperparathyroidism. Conclusion. Hyperparathyroidism and hypercalcemia are risk factors for pancreatitis. Women who develop pancreatitis during pregnancy are at increased risk of developing preeclampsia. If elevated serum calcium is noted, it should be confirmed with ionized calcium level and parathyroid hormones as ionized calcium levels are unaffected by pregnancy. |
format | Online Article Text |
id | pubmed-5405398 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-54053982017-05-09 Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features Dale, Andrew G. Holbrook, Bradley D. Sobel, Lauren Rappaport, Valerie J. Case Rep Obstet Gynecol Case Report Background. Hyperparathyroidism is underdiagnosed in pregnancy, yet early diagnosis is necessary for the potentially severe sequelae of hypercalcemia for both the woman and fetus. Case. A 31-year-old, gravida 3, para 0-0-2-0 at 32 weeks and 3 days of gestation, presented with preeclampsia with severe features concomitant with acute pancreatitis and known diabetes mellitus type 2. She was stabilized and delivered. In the postpartum period, her total calcium level remained elevated. Ionized calcium levels and parathyroid hormone levels were also elevated, and she was diagnosed with hyperparathyroidism. Conclusion. Hyperparathyroidism and hypercalcemia are risk factors for pancreatitis. Women who develop pancreatitis during pregnancy are at increased risk of developing preeclampsia. If elevated serum calcium is noted, it should be confirmed with ionized calcium level and parathyroid hormones as ionized calcium levels are unaffected by pregnancy. Hindawi 2017 2017-04-11 /pmc/articles/PMC5405398/ /pubmed/28487796 http://dx.doi.org/10.1155/2017/6061313 Text en Copyright © 2017 Andrew G. Dale et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Dale, Andrew G. Holbrook, Bradley D. Sobel, Lauren Rappaport, Valerie J. Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features |
title | Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features |
title_full | Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features |
title_fullStr | Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features |
title_full_unstemmed | Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features |
title_short | Hyperparathyroidism in Pregnancy Leading to Pancreatitis and Preeclampsia with Severe Features |
title_sort | hyperparathyroidism in pregnancy leading to pancreatitis and preeclampsia with severe features |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405398/ https://www.ncbi.nlm.nih.gov/pubmed/28487796 http://dx.doi.org/10.1155/2017/6061313 |
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