Intestinal microbiota link lymphopenia to murine autoimmunity via PD-1(+)CXCR5(−/dim) B-helper T cell induction

T cell lymphopenia results in peripheral homeostatic expansion to maintain the T cell immune system, which is termed lymphopenia-induced proliferation (LIP). LIP is a potential risk for expanding autoreactive clones to become pathogenic in human and murine autoimmune diseases. However, the ontogeny...

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Detalles Bibliográficos
Autores principales: Eri, Toshiki, Kawahata, Kimito, Kanzaki, Takeyuki, Imamura, Mitsuru, Michishita, Kazuya, Akahira, Lisa, Bannai, Ei, Yoshikawa, Noritada, Kimura, Yasumasa, Satoh, Takeshi, Uematsu, Satoshi, Tanaka, Hirotoshi, Yamamoto, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405410/
https://www.ncbi.nlm.nih.gov/pubmed/28443628
http://dx.doi.org/10.1038/srep46037

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