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A unifying mathematical framework for experimental TCR-pMHC kinetic constants
Receptor binding and triggering are central in Immunology as T cells activated through their T cell receptors (TCR) by protein antigens orchestrate immune responses. In order to understand receptor-ligand interactions, many groups working with different experimental techniques and assays have genera...
Autores principales: | Faro, Jose, Castro, Mario, Molina-París, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405415/ https://www.ncbi.nlm.nih.gov/pubmed/28443634 http://dx.doi.org/10.1038/srep46741 |
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