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A unifying mathematical framework for experimental TCR-pMHC kinetic constants

Receptor binding and triggering are central in Immunology as T cells activated through their T cell receptors (TCR) by protein antigens orchestrate immune responses. In order to understand receptor-ligand interactions, many groups working with different experimental techniques and assays have genera...

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Detalles Bibliográficos
Autores principales: Faro, Jose, Castro, Mario, Molina-París, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405415/
https://www.ncbi.nlm.nih.gov/pubmed/28443634
http://dx.doi.org/10.1038/srep46741

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